Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome

• Published in: Microbiome Vol. 5; no. 1; pp. 44 - 17
• Main Authors: Nagy-Szakal, Dorottya, Williams, Brent L., Mishra, Nischay, Che, Xiaoyu, Lee, Bohyun, Bateman, Lucinda, Klimas, Nancy G., Komaroff, Anthony L., Levine, Susan, Montoya, Jose G., Peterson, Daniel L., Ramanan, Devi, Jain, Komal, Eddy, Meredith L., Hornig, Mady, Lipkin, W. Ian
• Format: Journal Article
• Language: English
• Published: England BioMed Central 26.04.2017; BMC
• Subjects: Abundance; Adult; Aged; Atrazine; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Biodegradation; Body mass; Body Mass Index; Chronic fatigue syndrome; Cognitive ability; Cytokines - blood; Dysbacteriosis; Fatigue; Fatigue Syndrome, Chronic - classification; Fatigue Syndrome, Chronic - immunology; Fatigue Syndrome, Chronic - microbiology; Feces - microbiology; Female; Fever; Humans; Intestine; Intolerance; Irritable bowel syndrome; Lymphadenopathy; Male; Metabolic Networks and Pathways; Metabolic pathways; Metabolites; Metagenomic; Metagenomics - methods; Microbiota-gut-brain axis; Middle Aged; Minority & ethnic groups; Morbidity; Motivation; Myalgic encephalomyelitis; Pain; Phylogeny; Topological data analysis; Vitamin B6; Young Adult; United States > US; Microbiota-gut-brain axis; Metagenomic; Irritable bowel syndrome; Metabolic pathway; Myalgic encephalomyelitis; Topological data analysis; Chronic fatigue syndrome

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained persistent fatigue, commonly accompanied by cognitive dysfunction, sleeping disturbances, orthostatic intolerance, fever, lymphadenopathy, and irritable bowel syndrome (IBS). The extent to which the gastroint...