The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 3; p. 607
• Main Authors: Wu, Jianbo, Miyasaka, Kenchi, Yamada, Wakana, Takeda, Shogo, Shimizu, Norihito, Shimoda, Hiroshi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 18.01.2022; MDPI
• Subjects: 3T3-L1 Cells; abdominal fat; Adipocytes; Adiposity; ampelopsin; Ampelopsis grossedentata; Animals; Anti-Obesity Agents - pharmacology; Antioxidants - pharmacology; Cholesterol; Decomposition; Diet; Diet, High-Fat; Dietary supplements; Enzymes; Fatty acids; Fatty liver; Fatty Liver, Alcoholic - drug therapy; Fatty Liver, Alcoholic - etiology; Fatty Liver, Alcoholic - metabolism; Fatty Liver, Alcoholic - pathology; Flavonoids - pharmacology; Glucose; Glycerol; Kinases; Lipid Metabolism; Lipids; Lipogenesis; Liver diseases; Male; Metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Obese; Non-alcoholic Fatty Liver Disease - drug therapy; Non-alcoholic Fatty Liver Disease - etiology; Non-alcoholic Fatty Liver Disease - metabolism; Non-alcoholic Fatty Liver Disease - pathology; Obesity; Obesity - drug therapy; Obesity - etiology; Obesity - metabolism; Obesity - pathology; Olive oil; Overweight; Phytotherapy; Plant Extracts - pharmacology; Rats; Rats, Sprague-Dawley; Tea - chemistry; vine tea; Weight control; ampelopsin; abdominal fat; fatty liver; obesity; Ampelopsis grossedentata; vine tea

Ampelopsis grossedentata (AG) is an ancient medicinal plant that is mainly distributed and used in southwest China. It exerts therapeutic effects, such as antioxidant, anti-diabetic, and anti-inflammatory activities, reductions in blood pressure and cholesterol and hepatoprotective effects. Research...