Antimicrobial Peptide Mastoparan-AF Kills Multi-Antibiotic Resistant Escherichia coli O157:H7 via Multiple Membrane Disruption Patterns and Likely by Adopting 3–11 Amphipathic Helices to Favor Membrane Interaction - Lin, Chun-Hsien; Shyu, Ching-Lin; Wu, Zong-Yen; Wang, Chao-Min; Chiou, Shiow-Her; Chen, Jiann-Yeu; Tseng, Shu-Ying; Lin, Ting-Er; Yuan, Yi-Po; Ho, Shu-Peng; Tung, Kwong-Chung; Mao, Frank Chiahung; et al. (Membranes (Basel), 2023)
Keywords: 5' Untranslated regions; Amino acids; Antibiotic resistance; Antibiotics; Anticoagulants; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; antimicrobial peptide; Antimicrobial peptides; Bacteria; Blood; Clinical isolates; Cloning; Disruption; Drug resistance; E coli; Escherichia coli; Escherichia coli O157:H7; Helices; Hydrophobicity; Lipids; Mastoparan; mastoparan-AF; membrane disruption pattern; membrane permeabilization; Membranes; Microscopy; Pathogens; Physicochemical properties; Polypeptides; Sodium; Tubes; Zoonoses; United States--US; Taiwan; Vespa affinis; antibiotic resistance; mastoparan-AF; membrane disruption pattern; membrane permeabilization; antimicrobial peptide; Escherichia coli O157:H7