Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 - Zhang, Qian; Bastard, Paul; Liu, Zhiyong; Le Pen, Jérémie; Moncada-Velez, Marcela; Chen, Jie; Ogishi, Masato; Sabli, Ira K. D.; Hodeib, Stephanie; Korol, Cecilia; Rosain, Jérémie; Bilguvar, Kaya; et al. (Science (American Association for the Advancement of Science), 2020)
Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Asymptomatic Infections; Betacoronavirus; Child; Child, Preschool; Coronavirus Infections - genetics; Coronavirus Infections - immunology; COVID-19; Female; Genetic Loci; Genetic Predisposition to Disease; Genetics; Human health and pathology; Humans; Immunology; Infant; Infectious diseases; Interferon Regulatory Factor-7 - deficiency; Interferon Regulatory Factor-7 - genetics; Interferon Type I - immunology; Life Sciences; Loss of Function Mutation; Male; Middle Aged; Online; Pandemics; Pneumonia, Viral - genetics; Pneumonia, Viral - immunology; Receptor, Interferon alpha-beta - deficiency; Receptor, Interferon alpha-beta - genetics; SARS-CoV-2; Toll-Like Receptor 3 - deficiency; Toll-Like Receptor 3 - genetics; Young Adult