Bioactive Peptides from Walnut Residue Protein

Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and oth...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 25; no. 6; p. 1285
Main Authors Li, Xiangyang, Guo, Manli, Chi, Jingtian, Ma, Jiangang
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 12.03.2020
MDPI
Subjects
Amino acids
antihypertensive activity
Antioxidants
Antioxidants - chemistry
Antioxidants - therapeutic use
antioxidation
bioactive peptide
Enzymes
Fatty acids
Fermentation
Food
Humans
Iron
Juglans - chemistry
Methods
Peptides
Peptides - chemistry
Peptides - genetics
Physiology
Plant Extracts - chemistry
Plant Extracts - therapeutic use
Plant Proteins - chemistry
preparation
Proteins
Raw materials
Review
walnut residue
Zinc
antioxidation
walnut residue
bioactive peptide
antihypertensive activity
preparation
Online AccessGet full text

Cover

Abstract Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and other materials. The uneconomical use of walnut residue has hindered the development of the walnut industry to some extent. Effective utilization of walnut residue protein to develop bioactive peptides and other products is of great significance to realize the comprehensive utilization of walnut residue, improve the added value of by-products, and change the current low utilization rate of walnut residue. In this paper, the preparation, purification and structure identification of walnut protein bioactive peptides are reviewed, and different functional walnut active peptides (WBPs) are introduced. The potential effects of these bioactivities on human health and their different uses in food, medicine and other industries are discussed. The purpose is to provide reference information for the effective utilization of walnut residue resources and the development of walnut industry.
AbstractList Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and other materials. The uneconomical use of walnut residue has hindered the development of the walnut industry to some extent. Effective utilization of walnut residue protein to develop bioactive peptides and other products is of great significance to realize the comprehensive utilization of walnut residue, improve the added value of by-products, and change the current low utilization rate of walnut residue. In this paper, the preparation, purification and structure identification of walnut protein bioactive peptides are reviewed, and different functional walnut active peptides (WBPs) are introduced. The potential effects of these bioactivities on human health and their different uses in food, medicine and other industries are discussed. The purpose is to provide reference information for the effective utilization of walnut residue resources and the development of walnut industry.Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and other materials. The uneconomical use of walnut residue has hindered the development of the walnut industry to some extent. Effective utilization of walnut residue protein to develop bioactive peptides and other products is of great significance to realize the comprehensive utilization of walnut residue, improve the added value of by-products, and change the current low utilization rate of walnut residue. In this paper, the preparation, purification and structure identification of walnut protein bioactive peptides are reviewed, and different functional walnut active peptides (WBPs) are introduced. The potential effects of these bioactivities on human health and their different uses in food, medicine and other industries are discussed. The purpose is to provide reference information for the effective utilization of walnut residue resources and the development of walnut industry.
Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as antioxidation and antihypertensive activity, but at present, walnut residue is often regarded as waste or low value feed, fertilizer and other materials. The uneconomical use of walnut residue has hindered the development of the walnut industry to some extent. Effective utilization of walnut residue protein to develop bioactive peptides and other products is of great significance to realize the comprehensive utilization of walnut residue, improve the added value of by-products, and change the current low utilization rate of walnut residue. In this paper, the preparation, purification and structure identification of walnut protein bioactive peptides are reviewed, and different functional walnut active peptides (WBPs) are introduced. The potential effects of these bioactivities on human health and their different uses in food, medicine and other industries are discussed. The purpose is to provide reference information for the effective utilization of walnut residue resources and the development of walnut industry.
Author Ma, Jiangang
Guo, Manli
Chi, Jingtian
Li, Xiangyang
AuthorAffiliation 1 Science and Technology Department, Hebei Lvlei Agroforestry Technology Co., Ltd. Shijiazhuang 050050, China
2 College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, China
AuthorAffiliation_xml – name: 2 College of Food Science and Engineering, Shandong Agricultural University, Taian 271018, China
– name: 1 Science and Technology Department, Hebei Lvlei Agroforestry Technology Co., Ltd. Shijiazhuang 050050, China
Author_xml – sequence: 1
  givenname: Xiangyang
  surname: Li
  fullname: Li, Xiangyang
– sequence: 2
  givenname: Manli
  surname: Guo
  fullname: Guo, Manli
– sequence: 3
  givenname: Jingtian
  surname: Chi
  fullname: Chi, Jingtian
– sequence: 4
  givenname: Jiangang
  surname: Ma
  fullname: Ma, Jiangang
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32178315$$D View this record in MEDLINE/PubMed
BookMark eNp1kktrVTEURoNU7EN_gBO54MTJbfN-TAQtPgoFRRSHISfZp-aSc3JNcgr-e9PetrQVR9lkr734SPYh2pvzDAi9JPiYMYNPppzALwkqFVgSqsUTdEA4xWuGudm7V--jw1o3GFPCiXiG9hklSjMiDtDx-5idb_ESVl9h22KAuhpLnlY_XZqXtvoGNYalN0tuEOfn6OnoUoUXN-cR-vHxw_fTz-vzL5_OTt-drz03rK35MGimnAaHaS9ADqCBBh60GIwIPshRhpE5wJTLEARgEMQYp5yCoE1gR-hs5w3Zbey2xMmVPza7aK8vcrmwrrToE1hiVGCDHugoBR-d1lIYqYBpo6UPwXXX251ruwwTBA9zKy49kD7szPGXvciXVhHOjFJd8OZGUPLvBWqzU6weUnIz5KVaypQyhiuGO_r6EbrJS5n7U11TGnPBWade3U90F-X2WzqgdoAvudYCo_WxuRbzVcCYLMH2agHsPwvQJ8mjyVv5_2f-Aq9QtfI
CitedBy_id crossref_primary_10_12677_hjfns_2025_141013
crossref_primary_10_1007_s13197_022_05372_w
crossref_primary_10_1016_j_fochx_2025_102217
crossref_primary_10_1016_j_foodchem_2024_138600
crossref_primary_10_1016_j_foodchem_2022_132943
crossref_primary_10_1039_D3FO00768E
crossref_primary_10_1039_D3FO04479C
crossref_primary_10_2174_0929867331666230703145043
crossref_primary_10_1016_j_lwt_2025_117549
crossref_primary_10_1080_10408398_2022_2054933
crossref_primary_10_1016_j_fbio_2024_105394
crossref_primary_10_1039_D3FO04403C
crossref_primary_10_3389_fendo_2022_1083707
crossref_primary_10_3390_gels9050376
crossref_primary_10_1021_acs_jafc_3c01620
crossref_primary_10_3390_nu15184085
crossref_primary_10_1002_sfp2_1013
crossref_primary_10_1002_fft2_210
crossref_primary_10_1007_s11694_023_02053_w
crossref_primary_10_1016_j_foodchem_2024_140027
crossref_primary_10_1111_jfbc_14414
crossref_primary_10_1111_1750_3841_15744
crossref_primary_10_1080_87559129_2022_2073367
crossref_primary_10_3390_ijms25179646
crossref_primary_10_1039_D3FO05076A
crossref_primary_10_1016_j_fochx_2024_101873
crossref_primary_10_12677_HJFNS_2022_114030
crossref_primary_10_2174_0929867330666230426111157
crossref_primary_10_1016_j_foodchem_2023_137905
crossref_primary_10_3390_nu16193277
crossref_primary_10_1016_j_jfutfo_2023_07_003
crossref_primary_10_1007_s10719_024_10156_9
crossref_primary_10_1016_j_foodchem_2024_138856
crossref_primary_10_3390_horticulturae9070782
crossref_primary_10_1016_j_foodchem_2021_130494
crossref_primary_10_3389_fnut_2022_889434
crossref_primary_10_3390_ijms241914853
crossref_primary_10_1016_j_foodchem_2025_143368
crossref_primary_10_1016_j_ifset_2023_103279
crossref_primary_10_3390_nu16162643
crossref_primary_10_1089_jmf_2023_K_0192
crossref_primary_10_1016_j_jff_2020_104068
crossref_primary_10_2174_0115734013314858240419052907
crossref_primary_10_1093_nutrit_nuae173
crossref_primary_10_1002_biof_1822
crossref_primary_10_1007_s10068_024_01600_5
crossref_primary_10_15690_pf_v22i1_2853
crossref_primary_10_1039_D3FO05501A
Cites_doi 10.1111/1756-185X.12007
10.3390/molecules21010072
10.1186/s12906-015-0940-9
10.2337/diacare.27.12.2777
10.1007/s13679-013-0067-6
10.1016/j.peptides.2012.09.017
10.3390/molecules24010045
10.1186/s13065-016-0184-x
10.1016/j.procbio.2017.05.010
10.1016/j.foodres.2018.08.068
10.1093/jn/130.2.171
10.3390/ijms13021561
10.1002/jsfa.9060
10.1016/j.lwt.2014.07.052
10.1080/10942912.2012.716476
10.1007/s10068-014-0265-3
10.3390/molecules23071775
10.1007/s00217-014-2227-7
10.3390/ijms19041156
10.1080/10942912.2016.1258574
10.3724/SP.J.1447.GOST.2018.18028
10.1093/rheumatology/kex422
10.3390/foods7100172
10.1021/acs.jafc.8b05722
10.1016/j.foodchem.2015.06.057
10.1016/j.enzmictec.2006.02.005
10.3109/0886022X.2011.653753
10.1016/j.fct.2008.02.002
10.1016/j.foodchem.2007.08.051
10.1016/j.idairyj.2005.12.012
10.1021/acs.jafc.8b03884
10.3945/jn.113.182907
10.3390/molecules24234260
10.1007/s12010-019-03109-8
10.1016/S0140-6736(05)17741-1
10.3168/jds.S0022-0302(00)74983-6
10.3390/foods6050032
10.1021/jf4001378
10.1002/jps.2600571009
10.1007/s00217-007-0737-2
10.3390/molecules17055661
10.1023/A:1008175606698
10.3390/nu9040316
10.1016/j.jff.2018.11.024
10.1021/acs.jafc.5b04924
10.1111/j.1582-4934.2009.00897.x
10.1007/s00217-015-2597-5
10.1016/j.foodres.2015.10.008
10.1016/j.cofs.2015.05.002
10.1016/j.peptides.2008.02.005
10.1002/qsar.200630005
10.1039/C7FO01174A
10.1016/j.jfca.2013.06.004
10.1002/1097-0010(200007)80:9<1393::AID-JSFA653>3.0.CO;2-F
10.1017/S0007114507837421
10.1089/jmf.2017.0063
10.1016/j.lwt.2018.01.061
10.1016/S1369-703X(02)00128-6
ContentType Journal Article
Copyright 2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2020 by the authors. 2020
Copyright_xml – notice: 2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2020 by the authors. 2020
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
DOA
DOI 10.3390/molecules25061285
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
AUTh Library subscriptions: ProQuest Central
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Health & Medical Collection (Alumni Edition)
Medical Database
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
Open Access: DOAJ - Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
MEDLINE

CrossRef
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
EISSN 1420-3049
ExternalDocumentID oai_doaj_org_article_197d3b8b2f654fa8865967e38986cdda
PMC7143977
32178315
10_3390_molecules25061285
Genre Journal Article
Review
GrantInformation_xml – fundername: The "13th Five-Year" national key development program of China
  grantid: 2018YFD0401100 and 2016YDF0401400
– fundername: Key R & D programs in Shandong, PR China
  grantid: 2018YYSP029
– fundername: The National Natural Science Foundation of China
  grantid: 31872889
GroupedDBID ---
0R~
123
2WC
53G
5VS
7X7
88E
8FE
8FG
8FH
8FI
8FJ
A8Z
AADQD
AAFWJ
AAHBH
AAYXX
ABDBF
ABUWG
ACGFO
ACIWK
ACPRK
ACUHS
AEGXH
AENEX
AFKRA
AFPKN
AFRAH
AFZYC
AIAGR
ALIPV
ALMA_UNASSIGNED_HOLDINGS
BENPR
BPHCQ
BVXVI
CCPQU
CITATION
CS3
D1I
DIK
DU5
E3Z
EBD
EMOBN
ESX
FYUFA
GROUPED_DOAJ
GX1
HH5
HMCUK
HYE
HZ~
I09
IHR
KQ8
LK8
M1P
MODMG
O-U
O9-
OK1
P2P
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
RPM
SV3
TR2
TUS
UKHRP
~8M
3V.
ABJCF
BBNVY
BHPHI
CGR
CUY
CVF
ECM
EIF
HCIFZ
KB.
M7P
M~E
NPM
PDBOC
7XB
8FK
AZQEC
DWQXO
K9.
PJZUB
PKEHL
PPXIY
PQEST
PQUKI
PRINS
7X8
5PM
PUEGO
ID FETCH-LOGICAL-c493t-4bb837a8ea02837e6be8e2d4d85b95dcd6f6df3ae0246dd5e0e5199a7a7ed89d3
IEDL.DBID 7X7
ISSN 1420-3049
IngestDate Wed Aug 27 01:17:34 EDT 2025
Thu Aug 21 13:19:11 EDT 2025
Fri Jul 11 06:37:29 EDT 2025
Fri Jul 25 19:47:27 EDT 2025
Wed Feb 19 02:29:48 EST 2025
Tue Jul 01 01:16:39 EDT 2025
Thu Apr 24 23:01:57 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 6
Keywords antioxidation
walnut residue
bioactive peptide
antihypertensive activity
preparation
Language English
License https://creativecommons.org/licenses/by/4.0
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c493t-4bb837a8ea02837e6be8e2d4d85b95dcd6f6df3ae0246dd5e0e5199a7a7ed89d3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
OpenAccessLink https://www.proquest.com/docview/2377804543?pq-origsite=%requestingapplication%
PMID 32178315
PQID 2377804543
PQPubID 2032355
ParticipantIDs doaj_primary_oai_doaj_org_article_197d3b8b2f654fa8865967e38986cdda
pubmedcentral_primary_oai_pubmedcentral_nih_gov_7143977
proquest_miscellaneous_2377994730
proquest_journals_2377804543
pubmed_primary_32178315
crossref_citationtrail_10_3390_molecules25061285
crossref_primary_10_3390_molecules25061285
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20200312
PublicationDateYYYYMMDD 2020-03-12
PublicationDate_xml – month: 3
  year: 2020
  text: 20200312
  day: 12
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Molecules (Basel, Switzerland)
PublicationTitleAlternate Molecules
PublicationYear 2020
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
References Sheng (ref_44) 2019; 67
Gheita (ref_64) 2012; 15
Kearney (ref_55) 2005; 365
Gu (ref_12) 2015; 60
Carrillo (ref_22) 2017; 20
ref_54
Pardo (ref_11) 2018; 91
ref_51
Iwamoto (ref_8) 2000; 130
Wattanasiritham (ref_50) 2016; 192
ref_15
ref_59
Wang (ref_41) 2014; 239
Mao (ref_16) 2012; 13
Wu (ref_35) 2014; 23
ref_61
Pereira (ref_3) 2008; 46
Labuckas (ref_1) 2010; 90
Yang (ref_33) 2019; 40
Jahanbani (ref_58) 2016; 71
Sathe (ref_13) 2000; 80
ref_23
Savage (ref_14) 2001; 56
Chakrabarti (ref_45) 2014; 2014
Oshima (ref_57) 1979; 566
Zheng (ref_36) 2017; 20
ref_29
Mienda (ref_39) 2011; 2
Stamp (ref_66) 2017; 57
ref_28
ref_27
Bhargava (ref_6) 1968; 57
Liu (ref_40) 2013; 61
Li (ref_68) 2018; 9
Daliri (ref_71) 2017; 6
Chen (ref_42) 2013; 34
ref_70
Tapia (ref_4) 2013; 31
Lv (ref_26) 2017; 59
Khan (ref_2) 2017; 7
Clare (ref_18) 2000; 83
ref_31
Diaz (ref_38) 2006; 39
Zhao (ref_67) 2015; 31
Lin (ref_49) 2010; 14
Ren (ref_53) 2018; 98
(ref_10) 2014; 144
Li (ref_69) 2019; 53
Tapsell (ref_9) 2004; 27
Labuckas (ref_5) 2008; 107
Fang (ref_46) 2018; 1
Feng (ref_21) 2019; 116
Gu (ref_24) 2015; 18
Aguilar (ref_37) 2003; 13
ref_47
Papoutsi (ref_7) 2008; 99
Liu (ref_25) 2016; 10
Filiopoulos (ref_65) 2012; 34
Wang (ref_20) 2016; 242
Zhang (ref_30) 2012; 17
Fang (ref_56) 2008; 29
Arranz (ref_17) 2008; 227
Chen (ref_19) 2012; 38
Borghi (ref_63) 2013; 2
Wang (ref_48) 2018; 66
Wu (ref_60) 2006; 25
Aluko (ref_62) 2015; 4
Chen (ref_43) 2015; 78
Quiros (ref_52) 2007; 17
Yan (ref_34) 2016; 37
Liao (ref_32) 2016; 64
References_xml – volume: 15
  start-page: 521
  year: 2012
  ident: ref_64
  article-title: Insulin resistance and metabolic syndrome in primary gout: Relation to punched-out erosions
  publication-title: Int. J. Rheum. Dis.
  doi: 10.1111/1756-185X.12007
– ident: ref_51
  doi: 10.3390/molecules21010072
– volume: 37
  start-page: 190
  year: 2016
  ident: ref_34
  article-title: Polypeptide Production from Cold-Pressed Walnut Meal by Liquid-State Fermentation
  publication-title: Food Sci.
– volume: 90
  start-page: 1959
  year: 2010
  ident: ref_1
  article-title: Walnut (Juglans regia L.): Genetic resources, chemistry, by-products
  publication-title: J. Sci. Food Agric.
– ident: ref_47
  doi: 10.1186/s12906-015-0940-9
– volume: 27
  start-page: 2777
  year: 2004
  ident: ref_9
  article-title: Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes
  publication-title: Diabetes Care
  doi: 10.2337/diacare.27.12.2777
– volume: 71
  start-page: 1
  year: 2016
  ident: ref_58
  article-title: Antioxidant and anticancer activities of walnut (juglans regia l.) protein hydrolysates using different proteases
  publication-title: Foods Hum. Nutr.
– volume: 2
  start-page: 301
  year: 2013
  ident: ref_63
  article-title: Increased Serum Uric Acid as a Risk Factor for Cardiovascular Diseases
  publication-title: Curr. Obes. Rep.
  doi: 10.1007/s13679-013-0067-6
– volume: 38
  start-page: 344
  year: 2012
  ident: ref_19
  article-title: Purification and identification of antioxidant peptides from walnut (Juglans regia L.) protein hydrolysates
  publication-title: Peptides
  doi: 10.1016/j.peptides.2012.09.017
– ident: ref_54
  doi: 10.3390/molecules24010045
– volume: 10
  start-page: 39
  year: 2016
  ident: ref_25
  article-title: A simple and convenient method for the preparation of antioxidant peptides from walnut (Juglansregia L.) protein hydrolysates
  publication-title: Chem. Cent. J.
  doi: 10.1186/s13065-016-0184-x
– volume: 59
  start-page: 223
  year: 2017
  ident: ref_26
  article-title: Separation and identification of iron-chelating peptides from defatted walnut flake by nanoLC-ESI-MS/MS and de novo sequencing
  publication-title: Proc. Biochem.
  doi: 10.1016/j.procbio.2017.05.010
– volume: 116
  start-page: 518
  year: 2019
  ident: ref_21
  article-title: Identification and characterization of antioxidative peptides derived from simulated in vitro gastrointestinal digestion of walnut meal proteins
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2018.08.068
– volume: 130
  start-page: 171
  year: 2000
  ident: ref_8
  article-title: Walnuts lower serum cholesterol in Japanese men and women
  publication-title: J. Nutr.
  doi: 10.1093/jn/130.2.171
– volume: 13
  start-page: 1561
  year: 2012
  ident: ref_16
  article-title: Composition, structure and functional properties of protein concentrates and isolates produced from walnut (Juglans regia L.)
  publication-title: Int. J. Mol. Sci.
  doi: 10.3390/ijms13021561
– volume: 98
  start-page: 5142
  year: 2018
  ident: ref_53
  article-title: Antioxidant hydrolyzed peptides from Manchurian walnut (Juglansmandshurica Maxim.) attenuate scopolamine-induced memory impairment in mice
  publication-title: J. Sci. Food Agr.
  doi: 10.1002/jsfa.9060
– volume: 60
  start-page: 213
  year: 2015
  ident: ref_12
  article-title: Identification of antioxidant peptides released from defatted walnut (Juglans Sigillata Dode) meal proteins with pancreatin
  publication-title: LWT-Food Sci. Technol.
  doi: 10.1016/j.lwt.2014.07.052
– volume: 18
  start-page: 266
  year: 2015
  ident: ref_24
  article-title: Separation, purification, and identification of angiotensin I–converting enzyme inhibitory peptides from walnut (Juglansregia L.) hydrolyzate
  publication-title: Int. J. Food Prop.
  doi: 10.1080/10942912.2012.716476
– volume: 23
  start-page: 1941
  year: 2014
  ident: ref_35
  article-title: Optimization of production conditions for antioxidant peptides from walnut protein meal using solid-state fermentation
  publication-title: Food Sci. Biotech.
  doi: 10.1007/s10068-014-0265-3
– ident: ref_29
  doi: 10.3390/molecules23071775
– volume: 239
  start-page: 333
  year: 2014
  ident: ref_41
  article-title: Purification and identification of an ACE-inhibitory peptide from walnut protein hydrolysate
  publication-title: Eur. Food Res. Technol.
  doi: 10.1007/s00217-014-2227-7
– volume: 2014
  start-page: 608979
  year: 2014
  ident: ref_45
  article-title: Food-Derived Bioactive Peptides on Inflammation and Oxidative Stress
  publication-title: J. Biomed. Biotechnol.
– ident: ref_23
  doi: 10.3390/ijms19041156
– volume: 20
  start-page: S3326
  year: 2017
  ident: ref_36
  article-title: Purification and identification of angiotensin I-converting enzyme inhibitory peptides from fermented walnut residues
  publication-title: Int. J. Food Prop.
  doi: 10.1080/10942912.2016.1258574
– volume: 1
  start-page: 44
  year: 2018
  ident: ref_46
  article-title: Antifatigue, Antioxidant and Immunoregulatory Effects of Peptides Hydrolyzed from Manchurian Walnut (Juglans mandshurica Maxim.) on Mice
  publication-title: Grain Oil Sci. Tech.
  doi: 10.3724/SP.J.1447.GOST.2018.18028
– volume: 57
  start-page: i35
  year: 2017
  ident: ref_66
  article-title: How to prevent allopurinol hypersensitivity reactions?
  publication-title: Rheumatology
  doi: 10.1093/rheumatology/kex422
– ident: ref_31
  doi: 10.3390/foods7100172
– volume: 67
  start-page: 3305
  year: 2019
  ident: ref_44
  article-title: Antioxidative effects and mechanism study of bioactive peptides from defatted walnut (Juglans regia L.) meal hydrolysate
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.8b05722
– volume: 192
  start-page: 156
  year: 2016
  ident: ref_50
  article-title: Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein
  publication-title: Food. Chem.
  doi: 10.1016/j.foodchem.2015.06.057
– volume: 39
  start-page: 1042
  year: 2006
  ident: ref_38
  article-title: Lipase from the thermotolerant fungus Rhizopushomothallicus is more thermostable when produced using solid state fermentation than liquid fermentation procedures
  publication-title: Enzyme Microb. Tech.
  doi: 10.1016/j.enzmictec.2006.02.005
– volume: 566
  start-page: 128
  year: 1979
  ident: ref_57
  article-title: Peptide inhibitors of angiotensin I-converting enzyme in digests of gelatin by bacterial collagenase
  publication-title: BBA-Bioenergetics
– ident: ref_59
– volume: 34
  start-page: 510
  year: 2012
  ident: ref_65
  article-title: New insights into uric acid effects on the progression and prognosis of chronic kidney disease
  publication-title: Ren. Fail.
  doi: 10.3109/0886022X.2011.653753
– volume: 2
  start-page: 21
  year: 2011
  ident: ref_39
  article-title: Microbiological features of solid state fermentation and its applications-An overview
  publication-title: Res. Biotechnol.
– volume: 46
  start-page: 2103
  year: 2008
  ident: ref_3
  article-title: Bioactive properties and chemical composition of six walnut (Juglans regia L.) cultivars
  publication-title: Food Chem. Toxicol.
  doi: 10.1016/j.fct.2008.02.002
– volume: 107
  start-page: 607
  year: 2008
  ident: ref_5
  article-title: Phenolics from walnut (Juglans regia L.) kernels: Antioxidant activity and interactions with proteins
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2007.08.051
– volume: 40
  start-page: 57
  year: 2019
  ident: ref_33
  article-title: Antibacterial activity and structural characterization of peach kernelpeptide-ferrous chelate
  publication-title: Food Sci.
– volume: 17
  start-page: 42
  year: 2007
  ident: ref_52
  article-title: Identification of bioactive peptides after digestion of human milk and infant formula with pepsin and pancreatin
  publication-title: Int. Dairy J.
  doi: 10.1016/j.idairyj.2005.12.012
– volume: 66
  start-page: 10617
  year: 2018
  ident: ref_48
  article-title: Walnut (Juglans regia) peptides reverse sleep deprivation-induced memory impairment in rat via alleviating oxidative stress
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.8b03884
– volume: 144
  start-page: 547S
  year: 2014
  ident: ref_10
  article-title: Walnuts decrease risk of cardiovascular disease: A summary of efficacy and biologic mechanisms
  publication-title: J. Nutr.
  doi: 10.3945/jn.113.182907
– ident: ref_27
  doi: 10.3390/molecules24234260
– volume: 34
  start-page: 72
  year: 2013
  ident: ref_42
  article-title: Preparation and Antioxidant Activities of Walnut Protein Hydrolysates
  publication-title: Chem. J. Chin. Univ.
– volume: 7
  start-page: 555709
  year: 2017
  ident: ref_2
  article-title: Screening and evaluation of exotic and indigenous walnut genotype and varieties
  publication-title: Agric. Res. Tech.
– volume: 31
  start-page: 291
  year: 2015
  ident: ref_67
  article-title: Technology optimization on preparation of XOD inhibition peptide from Saury
  publication-title: Trans. CSAE
– ident: ref_28
  doi: 10.1007/s12010-019-03109-8
– volume: 365
  start-page: 217
  year: 2005
  ident: ref_55
  article-title: Global burden of hypertension: Analysis of worldwide data
  publication-title: Lancet
  doi: 10.1016/S0140-6736(05)17741-1
– volume: 83
  start-page: 1187
  year: 2000
  ident: ref_18
  article-title: Bioactive milk peptides: A prospectus
  publication-title: J. Dairy Sci.
  doi: 10.3168/jds.S0022-0302(00)74983-6
– volume: 6
  start-page: 1
  year: 2017
  ident: ref_71
  article-title: Bioactive peptides
  publication-title: Foods
  doi: 10.3390/foods6050032
– volume: 61
  start-page: 4097
  year: 2013
  ident: ref_40
  article-title: Purification and identification of an ACE inhibitory peptide from walnut protein
  publication-title: Agric. Food Chem.
  doi: 10.1021/jf4001378
– volume: 57
  start-page: 1674
  year: 1968
  ident: ref_6
  article-title: Antitumor activity of Juglans nigra (black walnut) extractives
  publication-title: J. Pharm. Sci.
  doi: 10.1002/jps.2600571009
– volume: 227
  start-page: 425
  year: 2008
  ident: ref_17
  article-title: Antioxidant capacity of walnut (Juglans regia L.): Contribution of oil and defatted matter
  publication-title: Eur. Food Res. Technol.
  doi: 10.1007/s00217-007-0737-2
– volume: 17
  start-page: 5661
  year: 2012
  ident: ref_30
  article-title: Optimization of a microwave-coupled enzymatic digestion process to prepare peanut peptides
  publication-title: Molecules
  doi: 10.3390/molecules17055661
– volume: 56
  start-page: 75
  year: 2001
  ident: ref_14
  article-title: Chemical composition of walnuts (Juglans regia L.) grown in New Zealand
  publication-title: Plant Foods Hum. Nutr.
  doi: 10.1023/A:1008175606698
– ident: ref_61
  doi: 10.3390/nu9040316
– volume: 53
  start-page: 276
  year: 2019
  ident: ref_69
  article-title: Tryptophan residue enhances in vitro walnut protein-derived peptides exerting xanthine oxidase inhibition and antioxidant activities
  publication-title: J. Funct. Foods
  doi: 10.1016/j.jff.2018.11.024
– volume: 64
  start-page: 1509
  year: 2016
  ident: ref_32
  article-title: Synthesis and characterization of a walnut peptides–zinc complex and its antiproliferative activity against human breast carcinoma cells through the induction of apoptosis
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.5b04924
– volume: 14
  start-page: 840
  year: 2010
  ident: ref_49
  article-title: Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems
  publication-title: J. Cell Mol. Med.
  doi: 10.1111/j.1582-4934.2009.00897.x
– volume: 242
  start-page: 911
  year: 2016
  ident: ref_20
  article-title: Separation and purification of angiotensin-I-converting enzyme (ACE) inhibitory peptides from walnuts (Juglans regia L.) meal
  publication-title: Eur. Food Res. Technol.
  doi: 10.1007/s00217-015-2597-5
– volume: 78
  start-page: 216
  year: 2015
  ident: ref_43
  article-title: Show more Identification of antioxidative peptides from defatted walnut meal hydrolysate with potential for improving learning and memory
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2015.10.008
– volume: 4
  start-page: 44
  year: 2015
  ident: ref_62
  article-title: Structure and function of plant protein-derived antihypertensive peptides
  publication-title: Curr. Opin. Food Sci.
  doi: 10.1016/j.cofs.2015.05.002
– volume: 29
  start-page: 1062
  year: 2008
  ident: ref_56
  article-title: The antihypertensive effect of peptides: A novel alternative to drugs?
  publication-title: Peptides
  doi: 10.1016/j.peptides.2008.02.005
– volume: 25
  start-page: 873
  year: 2006
  ident: ref_60
  article-title: Structural requirements of angiotensin I-converting enzyme inhibitory peptides: Quantitative structure-activity relationship modeling of peptides containing 4-10 amino acid residues
  publication-title: QSAR Comb. Sci.
  doi: 10.1002/qsar.200630005
– volume: 9
  start-page: 107
  year: 2018
  ident: ref_68
  article-title: Moderation of hyperuricemia in rats via consuming walnut protein hydrolysate diet and identification of new antihyperuricemic peptides
  publication-title: Food Funct.
  doi: 10.1039/C7FO01174A
– ident: ref_15
– volume: 31
  start-page: 232
  year: 2013
  ident: ref_4
  article-title: Comparative study of the nutritional and bioactive compounds content of four walnut (Juglans regia L.) cultivars
  publication-title: J. Food Compos. Anal.
  doi: 10.1016/j.jfca.2013.06.004
– volume: 80
  start-page: 1393
  year: 2000
  ident: ref_13
  article-title: Walnuts (Juglans regia L): Proximate composition, protein solubility, protein amino acid composition and protein in vitro digestibility
  publication-title: J. Sci. Food Agric.
  doi: 10.1002/1097-0010(200007)80:9<1393::AID-JSFA653>3.0.CO;2-F
– ident: ref_70
– volume: 99
  start-page: 715
  year: 2008
  ident: ref_7
  article-title: Walnut extract (Juglans regia L.) and its component ellagic acid exhibit anti-inflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483
  publication-title: Br. J. Nutr.
  doi: 10.1017/S0007114507837421
– volume: 20
  start-page: 1063
  year: 2017
  ident: ref_22
  article-title: Antiproliferative activity of walnut (Juglans regia L.) proteins and walnut protein hydrolysates
  publication-title: J. Med. Food
  doi: 10.1089/jmf.2017.0063
– volume: 91
  start-page: 308
  year: 2018
  ident: ref_11
  article-title: Evaluation of physical parameters of walnut and walnut products obtained by cold pressing
  publication-title: LWT
  doi: 10.1016/j.lwt.2018.01.061
– volume: 13
  start-page: 157
  year: 2003
  ident: ref_37
  article-title: Advantages of fungal enzyme production in solid state over liquid fermentation systems
  publication-title: Biochem. Eng. J.
  doi: 10.1016/S1369-703X(02)00128-6
SSID ssj0021415
Score 2.5249853
SecondaryResourceType review_article
Snippet Walnut residue is a kind of high-quality plant protein resource. The bioactive peptide prepared from walnut residue has excellent health care functions such as...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage 1285
SubjectTerms Amino acids
antihypertensive activity
Antioxidants
Antioxidants - chemistry
Antioxidants - therapeutic use
antioxidation
bioactive peptide
Enzymes
Fatty acids
Fermentation
Food
Humans
Iron
Juglans - chemistry
Methods
Peptides
Peptides - chemistry
Peptides - genetics
Physiology
Plant Extracts - chemistry
Plant Extracts - therapeutic use
Plant Proteins - chemistry
preparation
Proteins
Raw materials
Review
walnut residue
Zinc
SummonAdditionalLinks – databaseName: Open Access: DOAJ - Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LS8QwEA7iRS_i2_qigiehuk3SPI66KIugiCh6K0kzxQXtirv7_51pu8uuil68NglMZ9J885HpfIwdK21doaRPfIbcRDodEqtAJiSYhmt4WhZEFG9uVe9RXj9nzzNSX1QT1rQHbhx3llodhDeelyqTpTNGZVZpQJw1qgihTo0Q8yZkqqVaKeJSc4cpkNSfvTVSszBEwEdIJ-HkGRSqm_X_lGF-LZScQZ6rVbbSpozxeWPqGluAap0tdSdKbRvs9KI_cPW5Fd9RkUqAYUy_jcRP7rUaj-J7wC03xkHqydCvNtnj1eVDt5e0OghJIa0YJdJ7pJHOgKNkQIPyYIAHGUzmbRaKoEoVSuEA8VaFkEEHMC-zTjsNwdggtthiNahgh8Vp6hwPpeedMpUlLuemQ8KlwpoACGYR60z8khdtk3DSqnjNkSyQK_NvrozYyXTJe9Mh47fJF-Ts6URqbl0_wJDnbcjzv0Iesf1JqPL2ixvmXGjqpZRJEbGj6TAGgi5AXAWDcTPHWomHWsS2m8hOLRHIzYxI0UI9F_M5U-dHqv5L3Y-bJOQxjd79j3fbY8ucGD1VDPJ9tjj6GMMBpj0jf1jv8E9q7ALg
  priority: 102
  providerName: Directory of Open Access Journals
Title Bioactive Peptides from Walnut Residue Protein
URI https://www.ncbi.nlm.nih.gov/pubmed/32178315
https://www.proquest.com/docview/2377804543
https://www.proquest.com/docview/2377994730
https://pubmed.ncbi.nlm.nih.gov/PMC7143977
https://doaj.org/article/197d3b8b2f654fa8865967e38986cdda
Volume 25
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB5Be4AL4k1KWQWJE1Loxnb8OCG26lIhUVUVFXuL7HhSVipJ2939_8wk2W0XUC85xLY0mnHmYU--D-CDNs5XWoUsFFSbKG9i5jSqjAnTaI3I64oLxe8n-vhcfZsVs-HAbTG0Va59YueoY1vxGfmBkIaxcgolP19dZ8waxberA4XGQ9hl6DJu6TKz24Irp-jU32RKKu0PfveEs7igsE-BnemT78SiDrL_f3nm3-2Sd-LP9Ck8GRLH9Etv6WfwAJvn8Ohwzdf2Aj5N5q3vvFd6yq0qERcp_zyS_vSXzWqZniFtvBUNMjLDvHkJ59OjH4fH2cCGkFXKyWWmQqBi0lv0nBIY1AEtiqiiLYIrYhV1rWMtPVLU1TEWOEbKzpw33mC0LspXsNO0Db6BNM-9F7EOYlznqqblwo6ZvlQ6G5FCWgLjtV7KaoAKZ8aKy5JKBlZl-Y8qE_i4WXLV42TcN3nCyt5MZIjr7kV7c1EOX0yZOxNlsEHUulC1t1YXThukBMvqKkafwP7aVOXw3S3K212SwPvNMBmCr0F8g-2qn-OcIteWwOveshtJJFVoVuYkodmy-Zao2yPN_FeHys1E8pRM790v1lt4LLhi545AsQ87y5sVvqO0ZhlG3d6lp51-HcHu5Ojk9GzUHRH8AXZK_cs
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VcigXRHkGWggSXJBCE9tx7AOqaGHZ0ocQakVvqR07sFJJSndXiD_V38hMXnQB9dZrbEfWvMcezwfwQmbaFFLYyKaYmwiTuUhLLyICTMM1LCkLShT3D-T4SHw8To-X4KJ_C0Nllb1NbAy1qws6I99gPKNeOangm2c_IkKNotvVHkKjFYtd_-snpmzTNzvvkL8vGRu9P9weRx2qQFQIzWeRsBaTMqO8IdeaeWm98swJp1KrU1c4WUpXcuPRe0nnUh97jHK0yUzmndKO439vwE3BuSaNUqMPQ4KXoDdsb05xMN743gLc-imGGRhIEFzzJd_XQAT8L679uzzzkr8b3YHbXaAavm0laxWWfHUXVrZ7fLh78HprUpvGWoafqDTG-WlIj1XCL-a0ms_Czx4FfY6D1AliUt2Ho2uh0wNYrurKP4IwSYxhrrQsLhNR4nKmYoJL5Vo5jy40gLinS150rckJIeM0xxSFSJn_Q8oAXg1Lztq-HFdN3iJiDxOppXbzoT7_mncamic6c9wqy0qZitIoJVMtM48BnZKFcyaAtZ5Veafn0_yPVAbwfBhGRtC1i6l8PW_naC3QlAbwsOXssBOOGaHiCe4wW-D5wlYXR6rJt6YLOAHXY_D--OptPYOV8eH-Xr63c7D7BG4xOi2gakS2Bsuz87lfx5BqZp82chzCyXUrzm8OQTkr
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIgEXxJtAgSDBBSlsYjt-HBCiLauWQlUhKvYW7NiBlUpSurtC_DV-HTN5bLuAeus1tiNr3mOP5wN4JpWxpRQucTnmJsIqnxgZREKAabiGZVVJieKHfblzKN5N8ska_B7ewlBZ5WATW0Ptm5LOyEeMK-qVkws-qvqyiIPt8evjHwkhSNFN6wCn0YnIXvj1E9O32avdbeT1c8bGbz9t7SQ9wkBSCsPniXAOEzSrgyU3q4J0QQfmhde5M7kvvaykr7gN6Mmk93lIA0Y8xiqrgtfGc_zvJbiseJ6RjqnJabKXoWfsblE5N-noewd2G2YYcmBQQdDNZ_xgCxfwvxj371LNM75vfAOu90Fr_KaTspuwFupbcHVrwIq7DS83p41tLWd8QGUyPsxiergSf7ZH9WIefwwo9AscpK4Q0_oOHF4Ine7Cet3U4T7EWWYt85VjaZWJCpcznRJ0KjfaB3SnEaQDXYqyb1NOaBlHBaYrRMriH1JG8GK55Ljr0XHe5E0i9nIitdduPzQnX4teW4vMKM-ddqySuais1jI3UgUM7rQsvbcRbAysKnqdnxWnEhrB0-UwMoKuYGwdmkU3xxiBZjWCex1nlzvhmB1qnuEO1QrPV7a6OlJPv7UdwQnEHgP5B-dv6wlcQZUp3u_u7z2Ea4wODqgwkW3A-vxkER5hdDV3j1sxjuHLRevNHyBOPVg
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Bioactive+Peptides+from+Walnut+Residue+Protein&rft.jtitle=Molecules+%28Basel%2C+Switzerland%29&rft.au=Li%2C+Xiangyang&rft.au=Guo%2C+Manli&rft.au=Chi%2C+Jingtian&rft.au=Ma%2C+Jiangang&rft.date=2020-03-12&rft.pub=MDPI&rft.eissn=1420-3049&rft.volume=25&rft.issue=6&rft_id=info:doi/10.3390%2Fmolecules25061285&rft_id=info%3Apmid%2F32178315&rft.externalDocID=PMC7143977
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1420-3049&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1420-3049&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1420-3049&client=summon