An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies

A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, fo...

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Published inMolecules (Basel, Switzerland) Vol. 24; no. 5; p. 907
Main Authors Park, Seungman, Tao, Jiaxiang, Sun, Li, Fan, Chen-Ming, Chen, Yun
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 05.03.2019
MDPI
Subjects
age
Animals
Biomedical materials
Design
Elastic Modulus
Elasticity
Equipment Design
Female
Homeostasis
Humans
indentation-based mechanical analyzer
Laboratories
Longitudinal Studies
Male
Mechanical Phenomena
Mechanical properties
Mechanics
Mice
Models, Theoretical
Prony model
Sensors
Skin cancer
Skin Physiological Phenomena
skin tissue
Stress, Mechanical
Tissue engineering
viscoelastic property
Viscoelasticity
Viscosity
United States > US
skin tissue
viscoelastic property
Prony model
indentation-based mechanical analyzer
age
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Abstract A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics.
AbstractList A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics.
A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics.A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than 100 USD and is capable of measuring samples of various geometry because of its modular design. The device is light-weight, thus portable, for measurements that can be performed at different sites. It was demonstrated that the measurement results obtained using our device are comparable to previous observations. The elastic shear modulus of the human skin was in the range of 2 kPa to 8 kPa, and skin tissues in old mice were stiffer than young mice. Mechanical properties of the skin tissues belonging to the same test subject varied depending on the location of the measurement. In conclusion, because our device is economic, modular, portable, and robust, it is suitable to serve as a standard measurement platform for studying tissue mechanics.
Author Tao, Jiaxiang
Chen, Yun
Sun, Li
Park, Seungman
Fan, Chen-Ming
AuthorAffiliation 3 Department of Bioinformatics, Southern University of Science and Technology, Shenzhen 518055, China; lisun97@foxmail.com
2 Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA; taojiaxiangjit9@gmail.com (J.T.); fan@carnegiescience.edu (C.-M.F.)
1 Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA; spark161@jhu.edu
AuthorAffiliation_xml – name: 2 Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA; taojiaxiangjit9@gmail.com (J.T.); fan@carnegiescience.edu (C.-M.F.)
– name: 1 Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA; spark161@jhu.edu
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Keywords skin tissue
viscoelastic property
Prony model
indentation-based mechanical analyzer
age
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Snippet A indentation-based device to measure tissue mechanical property was designed and built using over-the-counter and 3D-printed parts. The device costs less than...
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SubjectTerms age
Animals
Biomedical materials
Design
Elastic Modulus
Elasticity
Equipment Design
Female
Homeostasis
Humans
indentation-based mechanical analyzer
Laboratories
Longitudinal Studies
Male
Mechanical Phenomena
Mechanical properties
Mechanics
Mice
Models, Theoretical
Prony model
Sensors
Skin cancer
Skin Physiological Phenomena
skin tissue
Stress, Mechanical
Tissue engineering
viscoelastic property
Viscoelasticity
Viscosity
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Title An Economic, Modular, and Portable Skin Viscoelasticity Measurement Device for In Situ Longitudinal Studies
URI https://www.ncbi.nlm.nih.gov/pubmed/30841558
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Volume 24
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