Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice - Cheng, Ya-Yun; Chou, Ying-Tsen; Lai, Feng-Jie; Jan, Ming-Shiou; Chang, Tsung-Hao; Jou, I-Ming; Chen, Pei-Shiuan; Lo, Jui-Yen; Huang, Shiang-Suo; Chang, Nan-Shan; Liou, Yung-Tsai; Hsu, Po-Chih; et al. (Acta neuropathologica communications, 2020)
Keywords: Animals; Apoptosis; Ataxia; Brain; Brain - enzymology; Brain - pathology; Brain malformations; Cell Movement; Common chromosomal fragile site; Convulsions & seizures; Epilepsy; Epilepsy - enzymology; Epilepsy - genetics; Ethanol; Genes; Glycogen Synthase Kinase 3 beta - metabolism; Kinases; Metabolism; Mice, Knockout; Microscopy; Mutation; Neurodevelopmental disorders; Neurodevelopmental Disorders - enzymology; Neurodevelopmental Disorders - genetics; Neuronal degeneration; Neurons - pathology; Peripheral Nerves - ultrastructure; Phosphorylation; Proteins; Pyramidal Tracts - physiopathology; Rodents; Schwann cell apoptosis; Schwann Cells - pathology; Seizures - enzymology; Seizures - genetics; Transcription factors; WW Domain-Containing Oxidoreductase - genetics; Japan; Common chromosomal fragile site; Neuronal degeneration; Brain malformations; Schwann cell apoptosis; Epilepsy