Decontamination-Induced Modification of Bioactivity in Essential Oil-Based Plasma Polymer Coatings
Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain thei...
Saved in:
| Published in | Molecules (Basel, Switzerland) Vol. 26; no. 23; p. 7133 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Switzerland
MDPI AG
25.11.2021
MDPI |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the Melaleuca alternifolia polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20–30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against Staphylococcus aureus cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of Pseudomonas aeruginosa cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived P. aeruginosa bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations. |
|---|---|
| AbstractList | Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the Melaleuca alternifolia polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20–30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against Staphylococcus aureus cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of Pseudomonas aeruginosa cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived P. aeruginosa bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations. Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the Melaleuca alternifolia polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20–30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against Staphylococcus aureus cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of Pseudomonas aeruginosa cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived P. aeruginosa bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations. Plasma polymer coatings fabricated from essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20-30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations. Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the Melaleuca alternifolia polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20-30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against Staphylococcus aureus cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of Pseudomonas aeruginosa cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived P. aeruginosa bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations.Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium, polymers, and other implantable materials used in dentistry. Previous studies have shown these coatings to maintain their performance under standard operating conditions; however, when used in e.g., a dental implant, these coatings may inadvertently become subject to in situ cleaning treatments, such as those using an atmospheric pressure plasma jet, a promising tool for the effective in situ removal of biofilms from tissues and implant surfaces. Here, we investigated the effect of such an exposure on the antimicrobial performance of the Melaleuca alternifolia polymer coating. It was found that direct exposure of the polymer coating surface to the jet for periods less than 60 s was sufficient to induce changes in its surface chemistry and topography, affecting its ability to retard subsequent microbial attachment. The exact effect of the jet exposure depended on the chemistry of the polymer coating, the length of plasma treatment, cell type, and incubation conditions. The change in the antimicrobial activity for polymer coatings fabricated at powers of 20-30 W was not statistically significant due to their limited baseline bioactivity. Interestingly, the bioactivity of polymer coatings fabricated at 10 and 15 W against Staphylococcus aureus cells was temporarily improved after the treatment, which could be attributed to the generation of loosely attached bioactive fragments on the treated surface, resulting in an increase in the dose of the bioactive agents being eluted by the surface. Attachment and proliferation of Pseudomonas aeruginosa cells and mixed cultures were less affected by changes in the bioactivity profile of the surface. The sensitivity of the cells to the change imparted by the jet treatment was also found to be dependent on their origin culture, with mature biofilm-derived P. aeruginosa bacterial cells showing a greater ability to colonize the surface when compared to its planktonic broth-grown counterpart. The presence of plasma-generated reactive oxygen and nitrogen species in the culture media was also found to enhance the bioactivity of polymer coatings fabricated at power levels of 10 and 15 W, due to a synergistic effect arising from simultaneous exposure of cells to reactive oxygen and nitrogen species (RONS) and eluted bioactive fragments. These results suggest that it is important to consider the possible implications of inadvertent changes in the properties and performance of plasma polymer coatings as a result of exposure to in situ decontamination, to both prevent suboptimal performance and to exploit possible synergies that may arise for some polymer coating-surface treatment combinations. |
| Author | Crawford, Russell J. Levchenko, Igor Bazaka, Kateryna Ivanova, Elena P. Prasad, Karthika Jacob, Mohan V. Bazaka, Olha Kingshott, Peter |
| AuthorAffiliation | 4 College of Science & Engineering, James Cook University, Townsville, QLD 4810, Australia; mohan.jacob@jcu.edu.au 2 School of Engineering, The Australian National University, Canberra, ACT 2601, Australia; Karthika.Prasad@anu.edu.au (K.P.); katia.bazaka@anu.edu.au (K.B.) 6 Australian Research Council (ARC) Industrial Transformation Training Centre in Surface Engineering for Advanced Materials (SEAM), Swinburne University of Technology, Hawthorn, VIC 3122, Australia 3 Plasma Sources and Applications Centre, NIE, Nanyang Technological University, Singapore 637616, Singapore; levchenko.igor@nie.edu.sg 5 Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia; pkingshott@swin.edu.au 1 School of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia; s3729979@student.rmit.edu.au (O.B.); russell.crawford@rmit.edu.au (R.J.C.) |
| AuthorAffiliation_xml | – name: 6 Australian Research Council (ARC) Industrial Transformation Training Centre in Surface Engineering for Advanced Materials (SEAM), Swinburne University of Technology, Hawthorn, VIC 3122, Australia – name: 4 College of Science & Engineering, James Cook University, Townsville, QLD 4810, Australia; mohan.jacob@jcu.edu.au – name: 3 Plasma Sources and Applications Centre, NIE, Nanyang Technological University, Singapore 637616, Singapore; levchenko.igor@nie.edu.sg – name: 5 Department of Chemistry and Biotechnology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia; pkingshott@swin.edu.au – name: 1 School of Science, STEM College, RMIT University, Melbourne, VIC 3000, Australia; s3729979@student.rmit.edu.au (O.B.); russell.crawford@rmit.edu.au (R.J.C.) – name: 2 School of Engineering, The Australian National University, Canberra, ACT 2601, Australia; Karthika.Prasad@anu.edu.au (K.P.); katia.bazaka@anu.edu.au (K.B.) |
| Author_xml | – sequence: 1 givenname: Olha surname: Bazaka fullname: Bazaka, Olha – sequence: 2 givenname: Karthika surname: Prasad fullname: Prasad, Karthika – sequence: 3 givenname: Igor orcidid: 0000-0002-8606-6195 surname: Levchenko fullname: Levchenko, Igor – sequence: 4 givenname: Mohan V. orcidid: 0000-0002-2598-7193 surname: Jacob fullname: Jacob, Mohan V. – sequence: 5 givenname: Kateryna surname: Bazaka fullname: Bazaka, Kateryna – sequence: 6 givenname: Peter surname: Kingshott fullname: Kingshott, Peter – sequence: 7 givenname: Russell J. surname: Crawford fullname: Crawford, Russell J. – sequence: 8 givenname: Elena P. orcidid: 0000-0002-5509-8071 surname: Ivanova fullname: Ivanova, Elena P. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34885713$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kkFv1DAQhS1URNttfwAXFIlLLwE7dhLngkSXAiu1ag_0bE3syeKVYxc7qbT_HrNbqrZInGyNv_c0zzPH5MAHj4S8ZfQD5x39OAaHenaYqqbiLeP8FTlioqIlp6I7eHI_JMcpbSitmGD1G3LIhZR1FhyR_gvq4CcYrYfJBl-uvJk1muIqGDtYvSsWYSjObQA92Xs7bQvri4uU0E8WXHFtXXkOKUtuHKQRipvgtiPGYhmy2K_TCXk9gEt4-nAuyO3Xix_L7-Xl9bfV8vNlqUXHp1K0g-lRGC1aoA3lEoe6lX3VygqxRl1xEJRxCpnjUlLeAEVTDQI1NhwlX5DV3tcE2Ki7aEeIWxXAql0hxLWCOFntUFVdP8i-N9i1IETL5SAaY0CaoUNE4Nnr097rbu5HNDpnjeCemT5_8fanWod7JZu6Y7zLBmcPBjH8mjFNarRJo3PgMcxJVQ2VdR5DTrQg71-gmzBHn79qRzEuWNdm6t3Tjh5b-TvKDLA9oGNIKeLwiDCq_qyL-mddsqZ9odF22o08h7LuP8rffdrJvQ |
| CitedBy_id | crossref_primary_10_1002_admt_202101471 crossref_primary_10_3390_nano12213822 crossref_primary_10_1002_ppap_202300016 crossref_primary_10_1021_acsami_4c08193 crossref_primary_10_1002_ppap_202300075 |
| Cites_doi | 10.3390/polym3010388 10.3390/ijms22073800 10.3390/nano7070170 10.1016/j.tibtech.2018.06.010 10.1371/journal.pone.0180507 10.1038/s41598-019-39414-9 10.1039/C4RA08187K 10.3390/molecules26164762 10.3390/nano11010182 10.1166/mex.2012.1086 10.1088/2399-1984/aa80d3 10.1016/j.apsusc.2014.07.009 10.1515/hsz-2018-0226 10.1021/acsami.6b00330 10.1007/s11090-019-10045-2 10.1021/acsami.9b03961 10.3390/coatings11010068 10.1016/j.apsusc.2020.146375 10.1021/la052143a 10.1016/j.polymdegradstab.2010.02.014 10.1038/srep38610 10.1038/srep45599 10.3390/ma13030586 10.1166/jnn.2014.9409 10.1021/bm100369n 10.1039/a806603e 10.3390/molecules26051418 10.3390/foods10081888 10.1073/pnas.1710996114 10.1007/s10570-019-02685-6 10.1557/jmr.2011.23 10.1039/C8TB01363B 10.1371/journal.pone.0155584 10.1002/ppap.201100097 10.1039/b816814h 10.1039/C8GC02800A 10.3390/ma9070515 10.1016/j.surfcoat.2018.05.074 10.1002/mame.202000694 |
| ContentType | Journal Article |
| Copyright | 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2021 by the authors. 2021 |
| Copyright_xml | – notice: 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2021 by the authors. 2021 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. M0S M1P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.3390/molecules26237133 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One ProQuest Central Korea Proquest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) ProQuest Health & Medical Collection Medical Database ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef Publicly Available Content Database MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1420-3049 |
| ExternalDocumentID | oai_doaj_org_article_29bf8bbde97a44738f46dda8df9eeea3 PMC8659139 34885713 10_3390_molecules26237133 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: Australian Government Research Training Program grantid: Scholarship – fundername: Australian Research Council grantid: DP180101254, DE130101550 |
| GroupedDBID | --- 0R~ 123 2WC 53G 5VS 7X7 88E 8FE 8FG 8FH 8FI 8FJ A8Z AADQD AAFWJ AAHBH AAYXX ABDBF ABUWG ACGFO ACIWK ACPRK ACUHS AEGXH AENEX AFKRA AFPKN AFRAH AFZYC AIAGR ALIPV ALMA_UNASSIGNED_HOLDINGS BENPR BPHCQ BVXVI CCPQU CITATION CS3 D1I DIK DU5 E3Z EBD EMOBN ESX FYUFA GROUPED_DOAJ GX1 HH5 HMCUK HYE HZ~ I09 IAO IHR ITC KQ8 LK8 M1P MODMG O-U O9- OK1 P2P PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO RPM SV3 TR2 TUS UKHRP ~8M 3V. ABJCF BBNVY BHPHI CGR CUY CVF ECM EIF HCIFZ KB. M7P M~E NPM PDBOC 7XB 8FK AZQEC DWQXO K9. PJZUB PKEHL PPXIY PQEST PQUKI PRINS 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c493t-47fdbe4dc47a06038ef578b2782ee5ec23a40130a7fd388036a0ed2f4ece63e83 |
| IEDL.DBID | 7X7 |
| ISSN | 1420-3049 |
| IngestDate | Wed Aug 27 01:31:48 EDT 2025 Thu Aug 21 18:20:50 EDT 2025 Sun Aug 24 04:07:56 EDT 2025 Fri Jul 25 09:30:52 EDT 2025 Wed Feb 19 02:27:18 EST 2025 Thu Apr 24 23:06:02 EDT 2025 Tue Jul 01 03:12:03 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 23 |
| Keywords | atmospheric pressure plasma plasma polymer antibacterial polymer coatings |
| Language | English |
| License | https://creativecommons.org/licenses/by/4.0 Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c493t-47fdbe4dc47a06038ef578b2782ee5ec23a40130a7fd388036a0ed2f4ece63e83 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-5509-8071 0000-0002-8606-6195 0000-0002-2598-7193 |
| OpenAccessLink | https://www.proquest.com/docview/2608134197?pq-origsite=%requestingapplication% |
| PMID | 34885713 |
| PQID | 2608134197 |
| PQPubID | 2032355 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_29bf8bbde97a44738f46dda8df9eeea3 pubmedcentral_primary_oai_pubmedcentral_nih_gov_8659139 proquest_miscellaneous_2608534801 proquest_journals_2608134197 pubmed_primary_34885713 crossref_primary_10_3390_molecules26237133 crossref_citationtrail_10_3390_molecules26237133 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20211125 |
| PublicationDateYYYYMMDD | 2021-11-25 |
| PublicationDate_xml | – month: 11 year: 2021 text: 20211125 day: 25 |
| PublicationDecade | 2020 |
| PublicationPlace | Switzerland |
| PublicationPlace_xml | – name: Switzerland – name: Basel |
| PublicationTitle | Molecules (Basel, Switzerland) |
| PublicationTitleAlternate | Molecules |
| PublicationYear | 2021 |
| Publisher | MDPI AG MDPI |
| Publisher_xml | – name: MDPI AG – name: MDPI |
| References | Bazaka (ref_25) 2014; 14 Dimitrakellis (ref_10) 2021; 306 ref_36 ref_32 Bazaka (ref_30) 2017; 7 Irfan (ref_8) 2019; 26 Bazaka (ref_23) 2011; 3 ref_19 ref_18 ref_15 ref_37 Bazaka (ref_39) 2012; 2 Lee (ref_4) 2019; 9 Dai (ref_34) 2018; 36 Kumar (ref_27) 2018; 349 Kostov (ref_29) 2014; 314 Cavallaro (ref_11) 2016; 8 Kumar (ref_13) 2020; 40 Vasilev (ref_7) 2011; 8 Zhou (ref_33) 2019; 11 Bazaka (ref_31) 2017; 1 ref_1 Zhou (ref_20) 2018; 20 ref_3 Akhavan (ref_9) 2018; 6 ref_2 Bazaka (ref_12) 2020; 521 Yick (ref_16) 2015; 5 Clauson (ref_17) 2016; 6 Bremmell (ref_38) 2006; 22 Bazaka (ref_21) 2011; 26 ref_26 Lu (ref_14) 2017; 114 Bazaka (ref_22) 2010; 11 ref_5 Bazaka (ref_24) 2010; 95 Jiang (ref_28) 2009; 19 ref_6 Kaushik (ref_35) 2019; 400 |
| References_xml | – volume: 3 start-page: 388 year: 2011 ident: ref_23 article-title: The effect of polyterpenol thin film surfaces on bacterial viability and adhesion publication-title: Polymers doi: 10.3390/polym3010388 – ident: ref_2 doi: 10.3390/ijms22073800 – ident: ref_15 doi: 10.3390/nano7070170 – volume: 36 start-page: 1183 year: 2018 ident: ref_34 article-title: The emerging role of gas plasma in oncotherapy publication-title: Trends Biotechnol. doi: 10.1016/j.tibtech.2018.06.010 – ident: ref_37 doi: 10.1371/journal.pone.0180507 – volume: 9 start-page: 1938 year: 2019 ident: ref_4 article-title: The antibacterial effect of non-thermal atmospheric pressure plasma treatment of titanium surfaces according to the bacterial wall structure publication-title: Sci. Rep. doi: 10.1038/s41598-019-39414-9 – volume: 5 start-page: 5142 year: 2015 ident: ref_16 article-title: The effects of plasma treatment on bacterial biofilm formation on vertically-aligned carbon nanotube arrays publication-title: RSC Adv. doi: 10.1039/C4RA08187K – ident: ref_19 doi: 10.3390/molecules26164762 – ident: ref_1 doi: 10.3390/nano11010182 – volume: 2 start-page: 285 year: 2012 ident: ref_39 article-title: Solubility and surface interactions of RF plasma polymerized polyterpenol thin films publication-title: Mater. Express doi: 10.1166/mex.2012.1086 – volume: 1 start-page: 025002 year: 2017 ident: ref_31 article-title: Plasma-potentiated small molecules—possible alternative to antibiotics? publication-title: Nano Futures doi: 10.1088/2399-1984/aa80d3 – volume: 314 start-page: 367 year: 2014 ident: ref_29 article-title: Surface modification of polymeric materials by cold atmospheric plasma jet publication-title: Appl. Surf. Sci. doi: 10.1016/j.apsusc.2014.07.009 – volume: 400 start-page: 39 year: 2019 ident: ref_35 article-title: Biological and medical applications of plasma-activated media, water and solutions publication-title: Biol. Chem. doi: 10.1515/hsz-2018-0226 – volume: 8 start-page: 6354 year: 2016 ident: ref_11 article-title: Antibiofouling properties of plasma-deposited oxazoline-based thin films publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.6b00330 – volume: 40 start-page: 339 year: 2020 ident: ref_13 article-title: Pulse plasma deposition of terpinen-4-ol: An insight into polymerization mechanism and enhanced antibacterial response of developed thin films publication-title: Plasma Chem. Plasma Process. doi: 10.1007/s11090-019-10045-2 – volume: 11 start-page: 20660 year: 2019 ident: ref_33 article-title: Microplasma bubbles: Reactive vehicles for biofilm dispersal publication-title: ACS Appl. Mater. Interfaces doi: 10.1021/acsami.9b03961 – ident: ref_3 doi: 10.3390/coatings11010068 – volume: 521 start-page: 146375 year: 2020 ident: ref_12 article-title: Effect of titanium surface topography on plasma deposition of antibacterial polymer coatings publication-title: Appl. Surf. Sci. doi: 10.1016/j.apsusc.2020.146375 – volume: 22 start-page: 313 year: 2006 ident: ref_38 article-title: Colloid probe AFM investigation of interactions between fibrinogen and PEG-like plasma polymer surfaces publication-title: Langmuir doi: 10.1021/la052143a – volume: 95 start-page: 1123 year: 2010 ident: ref_24 article-title: Post-deposition ageing reactions of plasma derived polyterpenol thin films publication-title: Polym. Degrad. Stab. doi: 10.1016/j.polymdegradstab.2010.02.014 – volume: 6 start-page: 38610 year: 2016 ident: ref_17 article-title: Gram positive and Gram negative bacteria differ in their sensitivity to cold plasma publication-title: Sci. Rep. doi: 10.1038/srep38610 – volume: 7 start-page: 45599 year: 2017 ident: ref_30 article-title: Photostability of plasma polymerized γ-terpinene thin films for encapsulation of OPV publication-title: Sci. Rep. doi: 10.1038/srep45599 – ident: ref_26 doi: 10.3390/ma13030586 – volume: 14 start-page: 8087 year: 2014 ident: ref_25 article-title: Polymer encapsulation of magnesium to control biodegradability and biocompatibility publication-title: J. Nanosci. Nanotechnol. doi: 10.1166/jnn.2014.9409 – volume: 11 start-page: 2016 year: 2010 ident: ref_22 article-title: Plasma-enhanced synthesis of bioactive polymeric coatings from monoterpene alcohols: A combined experimental and theoretical study publication-title: Biomacromolecules doi: 10.1021/bm100369n – ident: ref_36 doi: 10.1039/a806603e – ident: ref_5 doi: 10.3390/molecules26051418 – ident: ref_18 doi: 10.3390/foods10081888 – volume: 114 start-page: E9793 year: 2017 ident: ref_14 article-title: Enhanced antibacterial activity through the controlled alignment of graphene oxide nanosheets publication-title: Proc. Nat. Acad. Sci. USA doi: 10.1073/pnas.1710996114 – volume: 26 start-page: 8877 year: 2019 ident: ref_8 article-title: Antibacterial, highly hydrophobic and semi transparent Ag/plasma polymer nanocomposite coating on cotton fabric obtained by plasma based co-deposition publication-title: Cellulose doi: 10.1007/s10570-019-02685-6 – volume: 26 start-page: 1018 year: 2011 ident: ref_21 article-title: Optical and chemical properties of polyterpenol thin films deposited via plasma-enhanced chemical vapor deposition publication-title: J. Mater. Res. doi: 10.1557/jmr.2011.23 – volume: 6 start-page: 5845 year: 2018 ident: ref_9 article-title: Direct covalent attachment of silver nanoparticles on radical-rich plasma polymer films for antibacterial applications publication-title: J. Mater. Chem. B doi: 10.1039/C8TB01363B – ident: ref_32 doi: 10.1371/journal.pone.0155584 – volume: 8 start-page: 1010 year: 2011 ident: ref_7 article-title: Antibacterial surfaces and coatings produced by plasma techniques publication-title: Plasma Process. Polym. doi: 10.1002/ppap.201100097 – volume: 19 start-page: 2234 year: 2009 ident: ref_28 article-title: Surface oxygen in plasma polymerized films publication-title: J. Mater. Chem. doi: 10.1039/b816814h – volume: 20 start-page: 5276 year: 2018 ident: ref_20 article-title: Cold atmospheric plasma activated water as a prospective disinfectant: The crucial role of peroxynitrite publication-title: Green Chem. doi: 10.1039/C8GC02800A – ident: ref_6 doi: 10.3390/ma9070515 – volume: 349 start-page: 426 year: 2018 ident: ref_27 article-title: Biodegradable optically transparent terpinen-4-ol thin films for marine antifouling applications publication-title: Surf. Coat. Technol. doi: 10.1016/j.surfcoat.2018.05.074 – volume: 306 start-page: 2000694 year: 2021 ident: ref_10 article-title: Bactericidal action of smooth and plasma micro-nanotextured polymeric surfaces with varying wettability, enhanced by incorporation of a biocidal agent publication-title: Macromol. Mater. Eng. doi: 10.1002/mame.202000694 |
| SSID | ssj0021415 |
| Score | 2.364297 |
| Snippet | Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial... Plasma polymer coatings fabricated from essential oil and its derivatives have been previously shown to reduce the extent of microbial adhesion on titanium,... Plasma polymer coatings fabricated from Melaleuca alternifolia essential oil and its derivatives have been previously shown to reduce the extent of microbial... |
| SourceID | doaj pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 7133 |
| SubjectTerms | Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology antibacterial polymer coatings Antimicrobial agents Atmospheric Pressure atmospheric pressure plasma Biofilms Biological activity Biomedical materials Carbon Chemical reactions Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - pharmacology Dental Implants - microbiology Gram-positive bacteria Humans Hydrocarbons Melaleuca - chemistry Microorganisms Nitrogen Oils & fats Oils, Volatile - chemistry Oils, Volatile - pharmacology Plasma etching Plasma Gases plasma polymer Polyethylene terephthalate Polymerization Polymers Polymers - chemistry Prostheses and Implants Protective coatings Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - pathogenicity Staphylococcus aureus - drug effects Staphylococcus aureus - pathogenicity Surface chemistry Titanium - chemistry |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Na9wwEB1CLu2ltE0_3KZFgZwKIlpLtqVjd5sQCk1yaCA3I1kjurBrl-zm0H_fGdu7ZNPSXnKVZBiPRsx7aPQG4Nh5bQinKlkpH6UxKUrrUMloHV_mEmOIvdrnRXl-bb7eFDf3Wn1xTdggDzw47iR3IdkQIrrKG1Npm0wZo7cxOUT0vc4n5bwNmRqp1oTy0nCHqYnUnyyHVrO4yinbMy3byUK9WP_fEObDQsl7mefsOTwbIaP4PJj6AvawfQlPZptObQcQvjCrXXuuamE_S-7H0WAU37rIlUD9oOiSmM47fsfA7SLEvBWnK355RAEoLucLOaV8FsUVoemlF1fd4tcSb8Ws81wXvXoF12en32fncuydIBvj9FqaKsWAJjam8qpU2mKisxlyAgSIBTa59syslKd1rAejS68w5slgg6VGq1_Dftu1-BaExtAQrCmQsJ5JTQrOeWVMKF2uiIoXGaiNL-tmFBbn_haLmggGu7_-w_0ZfNp-8nNQ1fjX4ilv0HYhC2L3AxQm9Rgm9f_CJIPDzfbW4yld1cTlbC9oV2VwtJ2mzeNLE99idzesKTSL7GTwZoiGrSU0bAsyMYNqJ052TN2daec_eg1vWxYsyPruMf7tPTzNudJmMpF5cQj769s7_EBQaR0-9qfiNwiIGDM priority: 102 providerName: Directory of Open Access Journals |
| Title | Decontamination-Induced Modification of Bioactivity in Essential Oil-Based Plasma Polymer Coatings |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/34885713 https://www.proquest.com/docview/2608134197 https://www.proquest.com/docview/2608534801 https://pubmed.ncbi.nlm.nih.gov/PMC8659139 https://doaj.org/article/29bf8bbde97a44738f46dda8df9eeea3 |
| Volume | 26 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Nj9MwELVg9wAXxDeBpTISJyRr3dhJ7BOipWWFxFIhVuotsuPxUqlNlrZ74N8zk6RdCmgvOThONLLHnjee8RvG3lqnNOJUKQrpgtA6BmEsSBGMpWAuegyhZfs8z88u9Od5Nu8P3DZ9WuVuT2w36tBUdEZ-irjbtORjxfurn4KqRlF0tS-hcZcdE3UZpXQV8xuHa4jWqYtkKnTtT1ddwVnYpGjzyTk7sEUtZf__cObf6ZJ_2J_pQ_agB478QzfTj9gdqB-ze-NdvbYnzH8k33brKLeFRltQVY4KAv_SBMoHaht5E_lo0dBtBioawRc1n2zo_hGqIf-6WIoRWrXAZ4ipV47PmuWvFaz5uHGUHb15yi6mk-_jM9FXUBCVtmordBGDBx0qXTiZS2Ug4gr1KcICgAyqVDnyr6TDfsQKo3InIaRRQwW5AqOesaO6qeEF4wp8heAmA0R8OlbRW-uk1j63qUSHPEuY3I1lWfX04lTlYlmim0HDX_4z_Al7t__kquPWuK3ziCZo35FosduGZn1Z9qusTK2PxvsAtnBaF8pEnYfgTIgWABz-5GQ3vWW_VjfljWYl7M3-NU4ehU5cDc111ydTRLWTsOedNuwlwWaToYgJKw705EDUwzf14kfL5G3yjGhZX94u1it2P6VMmuFQpNkJO9qur-E1QqGtH7T6jk8z_TRgx6PJ-ezboD1W-A32DxEB |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1NbxMxELVKOZQL4ruhBYwEFySrztq7ax8QImlDSj_ooZV6W-z1LERKdtskFeqf4jcys5sNBFBvvdrOyvKMPW_i8XuMvbFOacSpUqTSBaF1EYSxIEUwli5zMWMINdvncTI805_P4_M19rN9C0Nlle2ZWB_UocrpP_IdxN2mJh9LP1xcClKNotvVVkKjcYsDuP6BKdvs_f4u2vdtFA32TvtDsVAVELm2ai50WgQPOuQ6dTKRykCBXusjDJUAMeSRcpRzSIfjiClFJU5CiAoNOSQKjMLv3mF3tVKWdpQZfFomeF2Mhs3NKXbKnUkjcAuzCDEGJYMrsa-WCPgfrv27PPOPeDd4wO4vgCr_2HjWQ7YG5SO20W_14R4zv0u59NxRLQ1ZV5AKSA6BH1WB6o_qRl4VvDeq6PUEiVTwUcn3ZvTeCd2efxmNRQ-jaOAniOEnjp9U4-sJTHm_clSNPXvCzm5lbZ-y9bIqYZNxBT5HMBUDIkxd5IW31kmtfWIjCV7FHSbbtczyBZ05qWqMM0xraPmzf5a_w94tf3LRcHncNLhHBloOJBruuqGafssWuzqLrC-M9wFs6rROlSl0EoIzobAA4PAj2615s8XZMMt-e3KHvV52o_HoqsaVUF01Y2JF1D4d9qzxhuVMsNnEOMUOS1f8ZGWqqz3l6HvNHG6SmGhgn988rVdsY3h6dJgd7h8fbLF7EVXxdLsiirfZ-nx6BS8Qhs39y9r3Oft625vtF1EsSvo |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1LbxMxELZKkYAL4s1CASPBBWkVZ-19-IAQSRq1FEoOVMptsddjiJTsliQV6l_j1zGzj5QA6q1X22tZnhnPN-vxN4y90kYqxKkiTIVxoVLehZkGEbpM02UuRgyuZvs8Tg5O1IdpPN1hv7q3MJRW2Z2J9UHtqoL-kfcQd2c1-Vja821axGQ0fnf6I6QKUnTT2pXTaFTkCM5_Yvi2ens4Qlm_jqLx_pfhQdhWGAgLpeU6VKl3FpQrVGpEImQGHjXYRug2AWIoImko_hAGxxFrikyMABd5BQUkEjKJ815j11MZ98nG0ulFsNdHz9jcokqpRW_RFLuFVYR4gwLDLT9Ylwv4H8b9O1XzD983vsNut6CVv2-07C7bgfIeuznsasXdZ3ZEcfXaUF4NSTqkiiAFOP6pcpSLVDfyyvPBrKKXFFSwgs9Kvr-it09oAvzzbB4O0KM6PkE8vzB8Us3PF7Dkw8pQZvbqATu5kr19yHbLqoTHjEuwBQKrGBBtKl94q7URStlERwKsjAMmur3Mi5banCpszHMMcWj783-2P2BvNp-cNrwelw0ekIA2A4mSu26olt_y1sLzSFufWetAp0apVGZeJc6ZzHkNAAYn2evEm7fnxCq_0OqAvdx0o_Do2saUUJ01Y2JJND8Be9Row2Yl2JzFuMSApVt6srXU7Z5y9r1mEc-SmChhn1y-rBfsBppZ_vHw-OgpuxVRQk-_H0bxHttdL8_gGSKytX1eqz5nX6_a1n4DNFVPJw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Decontamination-Induced+Modification+of+Bioactivity+in+Essential+Oil-Based+Plasma+Polymer+Coatings&rft.jtitle=Molecules+%28Basel%2C+Switzerland%29&rft.au=Bazaka%2C+Olha&rft.au=Prasad%2C+Karthika&rft.au=Levchenko%2C+Igor&rft.au=Jacob%2C+Mohan+V&rft.date=2021-11-25&rft.issn=1420-3049&rft.eissn=1420-3049&rft.volume=26&rft.issue=23&rft_id=info:doi/10.3390%2Fmolecules26237133&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1420-3049&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1420-3049&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1420-3049&client=summon |