Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial

• Published in: The Annals of thoracic surgery Vol. 75; no. 4; pp. 1097 - 1101
• Main Authors: Whyte, Richard I, Crownover, Richard, Murphy, Martin J, Martin, David P, Rice, Thomas W, DeCamp, Malcolm M, Rodebaugh, Raymond, Weinhous, Martin S, Le, Quynh-Thu
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.04.2003; Elsevier Science
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Feasibility Studies; Female; Follow-Up Studies; Humans; Lung Neoplasms - secondary; Lung Neoplasms - surgery; Male; Medical sciences; Middle Aged; Radiosurgery - adverse effects; Radiosurgery - methods; Safety; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; 10; Human; Lung disease; Prognosis; Respiratory disease; Treatment efficiency; Mortality; Instrumentation therapy; Intraoperative; Malignant tumor; Radiotherapy; Bronchopulmonary; Morbidity; Treatment; Surgery; Stereotaxic surgery; Phase I trial; Bronchus disease; Combined treatment; Technique

Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel. Twenty-three patients with biopsy-proven lung tumors were recruited into a two-institution, dose-escalation, phase I clinical trial using a frameless stereotactic radiosurg...