Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial
Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel. Twenty-three patients with biopsy-proven lung tumors were recruited into a two-institution, dose-escalation, phase I clinical trial using a frameless stereotactic radiosurg...
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Published in | The Annals of thoracic surgery Vol. 75; no. 4; pp. 1097 - 1101 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York, NY
Elsevier Inc
01.04.2003
Elsevier Science |
Subjects | |
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Abstract | Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel.
Twenty-three patients with biopsy-proven lung tumors were recruited into a two-institution, dose-escalation, phase I clinical trial using a frameless stereotactic radiosurgery system (CyberKnife). Fifteen patients had primary lung tumors and 8 had metastatic tumors. The age range was 23 to 87 years (mean, 63 years). After undergoing computed tomography–guided percutaneous placement of two to four small metal fiducials directly into the tumor, patients received 1,500 cGY of radiation in a single fraction using a linear accelerator mounted on a computer-controlled robotic arm. Safety, feasibility, and efficacy were studied.
Nine patients were treated with a breath-holding technique, and 14 with a respiratory-gating, automated, robotic technique. Tumor size ranged from 1 to 5 cm in maximal diameter. There were four complications related to fiducial placement: three pneumothoraces requiring chest tube insertion and one emphysema exacerbation. There were no grade 3 to 5 radiation-related complications. Follow-up ranged from 1 to 26 months (mean, 7.0 months). Radiographic response was scored as complete in 2 patients, partial in 15, stable in 4, and progressive in 2. Four patients died of non–treatment-related causes at 1, 5, 9, and 11 months after radiation.
Single-fraction stereotactic radiosurgery is safe and feasible for the treatment of selected lung tumors. Additional studies are planned to investigate the optimal radiation dose, best motion-suppression technique, and overall treatment efficacy. |
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AbstractList | Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel.
Twenty-three patients with biopsy-proven lung tumors were recruited into a two-institution, dose-escalation, phase I clinical trial using a frameless stereotactic radiosurgery system (CyberKnife). Fifteen patients had primary lung tumors and 8 had metastatic tumors. The age range was 23 to 87 years (mean, 63 years). After undergoing computed tomography-guided percutaneous placement of two to four small metal fiducials directly into the tumor, patients received 1,500 cGY of radiation in a single fraction using a linear accelerator mounted on a computer-controlled robotic arm. Safety, feasibility, and efficacy were studied.
Nine patients were treated with a breath-holding technique, and 14 with a respiratory-gating, automated, robotic technique. Tumor size ranged from 1 to 5 cm in maximal diameter. There were four complications related to fiducial placement: three pneumothoraces requiring chest tube insertion and one emphysema exacerbation. There were no grade 3 to 5 radiation-related complications. Follow-up ranged from 1 to 26 months (mean, 7.0 months). Radiographic response was scored as complete in 2 patients, partial in 15, stable in 4, and progressive in 2. Four patients died of non-treatment-related causes at 1, 5, 9, and 11 months after radiation.
Single-fraction stereotactic radiosurgery is safe and feasible for the treatment of selected lung tumors. Additional studies are planned to investigate the optimal radiation dose, best motion-suppression technique, and overall treatment efficacy. |
Author | Weinhous, Martin S Murphy, Martin J Whyte, Richard I Le, Quynh-Thu Martin, David P DeCamp, Malcolm M Rodebaugh, Raymond Rice, Thomas W Crownover, Richard |
Author_xml | – sequence: 1 givenname: Richard I surname: Whyte fullname: Whyte, Richard I email: riwhyte@stanford.edu organization: Departments of Cardiothoracic Surgery, Neurosurgery, and Radiation Oncology, Stanford University, Stanford, California, USA – sequence: 2 givenname: Richard surname: Crownover fullname: Crownover, Richard organization: Departments of Thoracic Surgery and Radiation Oncology, The Cleveland Clinic Medical Foundation, Cleveland, Ohio, USA – sequence: 3 givenname: Martin J surname: Murphy fullname: Murphy, Martin J organization: Departments of Cardiothoracic Surgery, Neurosurgery, and Radiation Oncology, Stanford University, Stanford, California, USA – sequence: 4 givenname: David P surname: Martin fullname: Martin, David P organization: Departments of Cardiothoracic Surgery, Neurosurgery, and Radiation Oncology, Stanford University, Stanford, California, USA – sequence: 5 givenname: Thomas W surname: Rice fullname: Rice, Thomas W organization: Departments of Thoracic Surgery and Radiation Oncology, The Cleveland Clinic Medical Foundation, Cleveland, Ohio, USA – sequence: 6 givenname: Malcolm M surname: DeCamp fullname: DeCamp, Malcolm M organization: Departments of Cardiothoracic Surgery, Neurosurgery, and Radiation Oncology, Stanford University, Stanford, California, USA – sequence: 7 givenname: Raymond surname: Rodebaugh fullname: Rodebaugh, Raymond organization: Departments of Thoracic Surgery and Radiation Oncology, The Cleveland Clinic Medical Foundation, Cleveland, Ohio, USA – sequence: 8 givenname: Martin S surname: Weinhous fullname: Weinhous, Martin S organization: Departments of Thoracic Surgery and Radiation Oncology, The Cleveland Clinic Medical Foundation, Cleveland, Ohio, USA – sequence: 9 givenname: Quynh-Thu surname: Le fullname: Le, Quynh-Thu organization: Departments of Cardiothoracic Surgery, Neurosurgery, and Radiation Oncology, Stanford University, Stanford, California, USA |
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Cites_doi | 10.1148/radiographics.15.4.7569143 10.1002/1097-0142(19850501)55:9+<2086::AID-CNCR2820551409>3.0.CO;2-1 10.3109/02841869509127197 10.2176/nmc.38.780 10.1016/S0360-3016(01)01703-5 10.3109/10929080009148894 10.1016/0003-4975(95)00537-U 10.1016/S0360-3016(98)80281-2 10.1159/000099863 10.1002/(SICI)1097-0142(19980315)82:6<1062::AID-CNCR8>3.0.CO;2-G |
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References | Wagner (BIB1) 2000 Uematsu, Shioda, Suda (BIB8) 2001; 51 Leksell (BIB2) 1951; 102 Blomgren, Lax, Naslund, Svanstrom (BIB7) 1995; 34 Chang, Murphy, Geis (BIB9) 1998; 38 Schweikard, Glosser, Bodduluri, Murphy, Adler (BIB5) 2000; 5 Antonuk, Yorkston, Huang (BIB4) 1995; 15 Takai, Mituya, Nemoto (BIB11) 2001; 61 Adler, Chang, Murphy (BIB3) 1997; 69 Klaus, Jurgen, Frank (BIB6) 1998; 42 Ginsberg, Rubinstein (BIB13) 1995; 60 Uematsu, Shioda, Tahara (BIB10) 1998; 82 Withers (BIB12) 1985; 55 Schweikard (10.1016/S0003-4975(02)04681-7_BIB5) 2000; 5 Takai (10.1016/S0003-4975(02)04681-7_BIB11) 2001; 61 Uematsu (10.1016/S0003-4975(02)04681-7_BIB8) 2001; 51 Chang (10.1016/S0003-4975(02)04681-7_BIB9) 1998; 38 Ginsberg (10.1016/S0003-4975(02)04681-7_BIB13) 1995; 60 Wagner (10.1016/S0003-4975(02)04681-7_BIB1) 2000 Antonuk (10.1016/S0003-4975(02)04681-7_BIB4) 1995; 15 Adler (10.1016/S0003-4975(02)04681-7_BIB3) 1997; 69 Leksell (10.1016/S0003-4975(02)04681-7_BIB2) 1951; 102 Withers (10.1016/S0003-4975(02)04681-7_BIB12) 1985; 55 Uematsu (10.1016/S0003-4975(02)04681-7_BIB10) 1998; 82 Blomgren (10.1016/S0003-4975(02)04681-7_BIB7) 1995; 34 Klaus (10.1016/S0003-4975(02)04681-7_BIB6) 1998; 42 |
References_xml | – volume: 55 start-page: 2086 year: 1985 end-page: 2095 ident: BIB12 article-title: Biologic basis for altered fractionation schemes publication-title: Cancer contributor: fullname: Withers – volume: 15 start-page: 993 year: 1995 end-page: 1000 ident: BIB4 article-title: A real-time, flat-panel, amorphous silicon, digital x-ray imager publication-title: Radiographics contributor: fullname: Huang – volume: 34 start-page: 861 year: 1995 end-page: 870 ident: BIB7 article-title: Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator publication-title: Acta Oncol contributor: fullname: Svanstrom – volume: 69 start-page: 124 year: 1997 end-page: 128 ident: BIB3 article-title: The Cyberknife publication-title: Stereotact Funct Neurosurg contributor: fullname: Murphy – volume: 82 start-page: 1062 year: 1998 end-page: 1070 ident: BIB10 article-title: Focal, high dose, and fractionated modified stereotactic radiation therapy for lung carcinoma patients publication-title: Cancer contributor: fullname: Tahara – volume: 60 start-page: 615 year: 1995 end-page: 623 ident: BIB13 article-title: Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer publication-title: Ann Thorac Surg contributor: fullname: Rubinstein – volume: 102 start-page: 316 year: 1951 end-page: 319 ident: BIB2 article-title: The stereotactic method and radiosurgery of the brain publication-title: Acta Chir Scand contributor: fullname: Leksell – volume: 51 start-page: 666 year: 2001 end-page: 670 ident: BIB8 article-title: Computed tomography-guided frameless stereotactic radiotherapy for stage I non-small cell lung cancer publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Suda – volume: 42 start-page: 214 year: 1998 ident: BIB6 article-title: Extracranial stereotactic conformal radiation therapy of tumors in the liver and the lung publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Frank – volume: 38 start-page: 780 year: 1998 end-page: 783 ident: BIB9 article-title: Clinical experience with image-guided robotic radiosurgery (the Cyberknife) in the treatment of brain and spinal cord tumors publication-title: Neurol Med Chir (Tokyo) contributor: fullname: Geis – volume: 61 start-page: 403 year: 2001 end-page: 407 ident: BIB11 article-title: Simple method of stereotactic radiotherapy without stereotactic body frame for extracranial tumors publication-title: Nippon Igaku Hoshasen Gakkai Zasshi contributor: fullname: Nemoto – volume: 5 start-page: 263 year: 2000 end-page: 277 ident: BIB5 article-title: Robotic motion compensation for respiratory movement during radiosurgery publication-title: Comp Aid Surg contributor: fullname: Adler – start-page: 829 year: 2000 end-page: 842 ident: BIB1 article-title: Resectable non-small cell lung cancer in the medically inoperable patient publication-title: Lung cancer: principles and practice contributor: fullname: Wagner – volume: 15 start-page: 993 year: 1995 ident: 10.1016/S0003-4975(02)04681-7_BIB4 article-title: A real-time, flat-panel, amorphous silicon, digital x-ray imager publication-title: Radiographics doi: 10.1148/radiographics.15.4.7569143 contributor: fullname: Antonuk – volume: 102 start-page: 316 year: 1951 ident: 10.1016/S0003-4975(02)04681-7_BIB2 article-title: The stereotactic method and radiosurgery of the brain publication-title: Acta Chir Scand contributor: fullname: Leksell – volume: 55 start-page: 2086 issue: Suppl 9 year: 1985 ident: 10.1016/S0003-4975(02)04681-7_BIB12 article-title: Biologic basis for altered fractionation schemes publication-title: Cancer doi: 10.1002/1097-0142(19850501)55:9+<2086::AID-CNCR2820551409>3.0.CO;2-1 contributor: fullname: Withers – volume: 34 start-page: 861 year: 1995 ident: 10.1016/S0003-4975(02)04681-7_BIB7 article-title: Stereotactic high dose fraction radiation therapy of extracranial tumors using an accelerator publication-title: Acta Oncol doi: 10.3109/02841869509127197 contributor: fullname: Blomgren – volume: 38 start-page: 780 year: 1998 ident: 10.1016/S0003-4975(02)04681-7_BIB9 article-title: Clinical experience with image-guided robotic radiosurgery (the Cyberknife) in the treatment of brain and spinal cord tumors publication-title: Neurol Med Chir (Tokyo) doi: 10.2176/nmc.38.780 contributor: fullname: Chang – volume: 51 start-page: 666 year: 2001 ident: 10.1016/S0003-4975(02)04681-7_BIB8 article-title: Computed tomography-guided frameless stereotactic radiotherapy for stage I non-small cell lung cancer publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(01)01703-5 contributor: fullname: Uematsu – volume: 61 start-page: 403 year: 2001 ident: 10.1016/S0003-4975(02)04681-7_BIB11 article-title: Simple method of stereotactic radiotherapy without stereotactic body frame for extracranial tumors publication-title: Nippon Igaku Hoshasen Gakkai Zasshi contributor: fullname: Takai – volume: 5 start-page: 263 year: 2000 ident: 10.1016/S0003-4975(02)04681-7_BIB5 article-title: Robotic motion compensation for respiratory movement during radiosurgery publication-title: Comp Aid Surg doi: 10.3109/10929080009148894 contributor: fullname: Schweikard – volume: 60 start-page: 615 year: 1995 ident: 10.1016/S0003-4975(02)04681-7_BIB13 article-title: Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer publication-title: Ann Thorac Surg doi: 10.1016/0003-4975(95)00537-U contributor: fullname: Ginsberg – volume: 42 start-page: 214 issue: Suppl 1 year: 1998 ident: 10.1016/S0003-4975(02)04681-7_BIB6 article-title: Extracranial stereotactic conformal radiation therapy of tumors in the liver and the lung publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/S0360-3016(98)80281-2 contributor: fullname: Klaus – volume: 69 start-page: 124 issue: 1–4 Pt 2 year: 1997 ident: 10.1016/S0003-4975(02)04681-7_BIB3 article-title: The Cyberknife publication-title: Stereotact Funct Neurosurg doi: 10.1159/000099863 contributor: fullname: Adler – start-page: 829 year: 2000 ident: 10.1016/S0003-4975(02)04681-7_BIB1 article-title: Resectable non-small cell lung cancer in the medically inoperable patient contributor: fullname: Wagner – volume: 82 start-page: 1062 year: 1998 ident: 10.1016/S0003-4975(02)04681-7_BIB10 article-title: Focal, high dose, and fractionated modified stereotactic radiation therapy for lung carcinoma patients publication-title: Cancer doi: 10.1002/(SICI)1097-0142(19980315)82:6<1062::AID-CNCR8>3.0.CO;2-G contributor: fullname: Uematsu |
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Snippet | Stereotactic radiosurgery is well established for the treatment of intracranial neoplasms but its use for lung tumors is novel.
Twenty-three patients with... |
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SubjectTerms | Adult Aged Aged, 80 and over Biological and medical sciences Feasibility Studies Female Follow-Up Studies Humans Lung Neoplasms - secondary Lung Neoplasms - surgery Male Medical sciences Middle Aged Radiosurgery - adverse effects Radiosurgery - methods Safety Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart |
Title | Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial |
URI | https://dx.doi.org/10.1016/S0003-4975(02)04681-7 https://www.ncbi.nlm.nih.gov/pubmed/12683544 |
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