HLA Class II ( DR , DQ, DP ) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07) - Zhao, Lue Ping; Papadopoulos, George K.; Skyler, Jay S.; Pugliese, Alberto; Parikh, Hemang M.; Kwok, William W.; Lybrand, Terry P.; Bondinas, George P.; Moustakas, Antonis K.; Wang, Ruihan; Pyo, Chul-Woo; Nelson, Wyatt C.; et al. (Diabetes care, 2024)
Keywords: Alleles; Autoantibodies; Autoimmunity; Clinical Medicine; Clinical trials; Diabetes; Diabetes mellitus (insulin dependent); Diabetes Mellitus, Type 1 - genetics; Diabetes Mellitus, Type 1 - prevention & control; Disease prevention; Disease Progression; DQA1 protein; Drb1 protein; Endocrinology and Diabetes; Endokrinologi och diabetes; Gene Frequency; Genes; Genotype; Haplotypes; Histocompatibility antigen HLA; HLA-DQ beta-Chains - genetics; HLA-DRB1 Chains - genetics; Humans; Immunogenicity; Klinisk medicin; Linkage disequilibrium; Medical and Health Sciences; Medicin och hälsovetenskap; Original; Pathogenesis; Regression models; Research design; Seroconversion