Concurrent Structural and Functional Patterns in Patients With Amnestic Mild Cognitive Impairment

• Published in: Frontiers in aging neuroscience Vol. 14; p. 838161
• Main Authors: Liu, Li, Wang, Tenglong, Du, Xiangdong, Zhang, Xiaobin, Xue, Chuang, Ma, Yu, Wang, Dong
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 17.05.2022; Frontiers Media S.A
• Subjects: Alzheimer's disease; amnestic mild cognitive impairment; amplitude of low-frequency fluctuations; Brain; Brain mapping; Cognitive ability; Cortex (cingulate); Data analysis; Dementia; Frontal gyrus; Functional magnetic resonance imaging; Magnetic resonance imaging; Memory; Morphometry; Neural networks; Neurodegenerative diseases; Neuroimaging; Neuroscience; Patients; Precentral gyrus; regional homogeneity; resting-state functional connectivity; Structure-function relationships; Substantia grisea; Superior temporal gyrus; Temporal cortex; Temporal gyrus; Temporal lobe; Time series; voxel-based morphometry; United States > US; resting-state functional connectivity; amplitude of low-frequency fluctuations; voxel-based morphometry; amnestic mild cognitive impairment; regional homogeneity

Amnestic mild cognitive impairment (aMCI) is a clinical subtype of MCI, which is known to have a high risk of developing Alzheimer's disease (AD). Although neuroimaging studies have reported brain abnormalities in patients with aMCI, concurrent structural and functional patterns in patients wit...