Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population

• Published in: BMC genomics Vol. 21; no. 1; p. 84
• Main Authors: Ng'oma, E, Williams-Simon, P A, Rahman, A, King, E G
• Format: Journal Article
• Language: English
• Published: England BioMed Central 28.01.2020; BMC
• Subjects: Aging; Biological activity; Cluster analysis; Clustering; Diet; Diet effects; Dietary restrictions; Differential gene expression; Drosophila melanogaster; Gene co-expression; Gene expression; Gene set enrichment; Gene set enrichment analysis; Genes; Genetic diversity; Genomics; Hormones; Insects; Insulin; Kinases; Metabolism; Modules; Multiparent population; Natural populations; Nucleotide sequence; Nutrient availability; Nutrients; Nutrition; Population; Populations; Principal components analysis; Resource allocation; Resource availability; Ribonucleic acid; RNA; Signal transduction; Tissues; Transcription; Transcription factors; Multiparent population; Diet effects; Gene co-expression; Gene set enrichment; Differential gene expression; Drosophila melanogaster

Environmental variation in the amount of resources available to populations challenge individuals to optimize the allocation of those resources to key fitness functions. This coordination of resource allocation relative to resource availability is commonly attributed to key nutrient sensing gene pat...