Zinc-Altered Immune function

• Published in: The Journal of nutrition Vol. 133; no. 5; pp. 1452S - 1456S
• Main Authors: Ibs, Klaus-Helge, Rink, Lothar
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Bethesda, MD Elsevier Inc 01.05.2003; American Institute of Nutrition; American Society for Nutritional Sciences
• Subjects: apoptosis; Biological and medical sciences; chemotaxis; cytokines; cytotoxicity; Dietary Supplements; Fundamental and applied biological sciences. Psychology; granulocytes; Humans; Immunity; immunology; interferon-gamma; interleukins; Killer Cells, Natural - immunology; leukocytes; monocytes; Monocytes - immunology; natural killer cells; Neutrophils - physiology; patients; Phagocytosis; T-lymphocytes; Trace Elements - physiology; tumor necrosis factor-alpha; zinc; Zinc - deficiency; Zinc - physiology; IFN; IL; TH; sIL; leukocytes; cytokines; zinc; immunology; NK; PBMC; TNF

Zinc is known to be essential for all highly proliferating cells in the human body, especially the immune system. A variety of in vivo and in vitro effects of zinc on immune cells mainly depend on the zinc concentration. All kinds of immune cells show decreased function after zinc depletion. In mono...