Apparent Diffusion Coefficient Signal Intensity Ratio Predicts the Effect of Revascularization on Ischemic Cerebral Edema

• Published in: Cerebrovascular diseases (Basel, Switzerland) Vol. 45; no. 3-4; p. 93
• Main Authors: Bevers, Matthew B, Battey, Thomas W K, Ostwaldt, Ann-Christin, Jahan, Reza, Saver, Jeffrey L, Kimberly, W Taylor, Kidwell, Chelsea S
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.2018
• Subjects: Aged; Aged, 80 and over; Brain Edema - diagnostic imaging; Brain Edema - etiology; Brain Edema - prevention & control; Brain Ischemia - complications; Brain Ischemia - diagnostic imaging; Brain Ischemia - physiopathology; Brain Ischemia - therapy; Diffusion Magnetic Resonance Imaging; Disability Evaluation; Embolectomy - adverse effects; Female; Humans; Male; Middle Aged; North America; Predictive Value of Tests; Recovery of Function; Risk Factors; Stroke - complications; Stroke - diagnostic imaging; Stroke - physiopathology; Stroke - therapy; Time Factors; Treatment Outcome; North America; Diffusion-weighted imaging; Acute stroke imaging; Cerebral edema; Acute ischemic stroke; MRI of acute stroke

Apparent diffusion coefficient (ADC) imaging is a biomarker of cytotoxic injury that predicts edema formation and outcome after ischemic stroke. It therefore has the potential to serve as a "tissue clock" to describe the extent of ischemic injury and potentially predict response to therapy...