Effect of Astaxanthin on the Inhibition of Lipid Accumulation in 3T3-L1 Adipocytes via Modulation of Lipogenesis and Fatty Acid Transport Pathways

• Published in: Molecules (Basel, Switzerland) Vol. 25; no. 16; p. 3598
• Main Authors: Tsai, Mei-Chih, Huang, Shih-Chien, Chang, Wei-Tang, Chen, Shiuan-Chih, Hsu, Chin-Lin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 07.08.2020; MDPI
• Subjects: 3T3-L1 adipocytes; 3T3-L1 Cells; Adipocytes; Adipocytes - cytology; Adipocytes - drug effects; Adipocytes - metabolism; Adipogenesis - drug effects; Animals; Antioxidants; astaxanthin; Biological Transport - drug effects; Cardiovascular disease; Carotenoids; Enzymes; Fatty acids; Fatty Acids - metabolism; Gene expression; Glycerol; Intracellular Space - drug effects; Intracellular Space - metabolism; Lipids; lipogenesis; Lipogenesis - drug effects; Lipoproteins; Metabolism; Mice; Obesity; Oxidative stress; Proteins; Triglycerides - metabolism; Xanthophylls - pharmacology; 3T3-L1 adipocytes; lipogenesis; gene expression; astaxanthin

Obesity is defined as a condition of excessive fat tissue accumulation. It was the major factor most closely associated with lifestyle-related diseases. In the present study, we investigated the effect of astaxanthin on the inhibition of lipid accumulation in 3T3-L1 adipocytes. 3T3-L1 adipocytes wer...