Repeatability and Reproducibility of in-vivo Brain Temperature Measurements

• Published in: Frontiers in human neuroscience Vol. 14; p. 598435
• Main Authors: Sharma, Ayushe A., Nenert, Rodolphe, Mueller, Christina, Maudsley, Andrew A., Younger, Jarred W., Szaflarski, Jerzy P.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 23.12.2020; Frontiers Media S.A
• Subjects: Alzheimer's disease; Biomarkers; Body temperature; Brain mapping; brain temperature; Chronic fatigue syndrome; Convulsions & seizures; Creatine; Epilepsy; Human Neuroscience; Magnetic resonance imaging; Magnetic resonance spectroscopy; Medical imaging; Metabolism; Metabolites; MR thermometry; MRS; Neuroimaging; neuroinflammation; Pathophysiology; Reproducibility; Spatial variations; MR thermometry; neuroinflammation; brain temperature; MRS; neuroimaging

Background: Magnetic resonance spectroscopic imaging (MRSI) is a neuroimaging technique that may be useful for non-invasive mapping of brain temperature (i.e., thermometry) over a large brain volume. To date, intra-subject reproducibility of MRSI-based brain temperature (MRSI-t) has not been investi...