A Combined Photochemical and Multicomponent Reaction Approach to Precision Oligomers

• Published in: Chemistry : a European journal Vol. 24; no. 14; pp. 3413 - 3419
• Main Authors: Konrad, Waldemar, Bloesser, Fabian R., Wetzel, Katharina S., Boukis, Andreas C., Meier, Michael A. R., Barner‐Kowollik, Christopher
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 07.03.2018; Wiley Subscription Services, Inc
• Subjects: Chains; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Conjugation; convergent; Dienes; Ionization; Ions; Magnetic resonance spectroscopy; Mass spectrometry; Mass spectroscopy; multicomponent reactions; NMR spectroscopy; Oligomers; Photochemical reactions; Photochemicals; photochemistry; Physical Sciences; Science & Technology; Sebacic acid; sequence control; sequence-defined macromolecules; Switching; sequence control; multicomponent reactions; ACRYLATE OLIGOMERS; ITERATIVE EXPONENTIAL-GROWTH; SOLID-PHASE SYNTHESIS; convergent; STRATEGY; sequence-defined macromolecules; COPOLYMERS; DENDRIMERS; SCALABLE SYNTHESIS; OLIGONUCLEOTIDES; photochemistry; POLYMER CHEMISTRY

We introduce the convergent synthesis of linear monodisperse sequence‐defined oligomers through a unique approach, combining the Passerini three‐component reaction (P‐3CR) and a Diels–Alder (DA) reaction based on photocaged dienes. A set of oligomers is prepared resting on a Passerini linker unit ca...