Visible Light—Responsive Drug Delivery Nanoparticle via Donor–Acceptor Stenhouse Adducts (DASA)

• Published in: Macromolecular rapid communications. Vol. 41; no. 21; pp. e2000236 - n/a
• Main Authors: Yap, Jeaniffer E., Zhang, Lin, Lovegrove, Jordan T., Beves, Jonathon E., Stenzel, Martina H.
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 01.11.2020
• Subjects: Adducts; Block copolymers; Breast cancer; donor–acceptor Stenhouse adducts; Drug delivery; Drug delivery systems; Fluorescence; Irradiation; Light irradiation; light‐responsive; Micelles; Nanoparticles; Polarity; Polyethylene glycol; Polymers; Protein adsorption; Radiation; Transmission electron microscopy

Stimuli‐responsive drug release from a nanocarrier triggered by light enables the control of the amount of drug locally. Here, block copolymer micelles based on poly(ethylene glycol) methyl ether methacrylate (PEGMEMA) as the hydrophilic block and a polymer with pendant donor–acceptor Stenhouse addu...