Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem

• Published in: Journal of comparative neurology (1911) Vol. 513; no. 4; pp. 349 - 362
• Main Authors: Toyoshima, Manabu, Sakurai, Kunie, Shimazaki, Kuniko, Takeda, Yasuo, Nakamoto, Masatoshi, Serizawa, Shou, Shimoda, Yasushi, Watanabe, Kazutada
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.04.2009
• Subjects: Animals; auditory pathway; Auditory Pathways - embryology; Auditory Pathways - growth & development; Auditory Pathways - metabolism; Blotting, Western; Brain Stem - embryology; Brain Stem - growth & development; Brain Stem - metabolism; Cell Adhesion Molecules, Neuronal - metabolism; contactin; Contactins; Glutamate Decarboxylase - metabolism; glutamatergic synapse; Glutamic Acid - metabolism; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Inbred C57BL; Neurons - metabolism; Neurons - ultrastructure; postnatal development; Rats; Rats, Wistar; Synapses - metabolism; Vesicular Glutamate Transport Protein 1 - metabolism; Vesicular Glutamate Transport Protein 2 - metabolism

NB‐2 is a neuronal cell recognition molecule that is preferentially expressed in auditory pathways. Mice deficient in the NB‐2 gene exhibit aberrant responses to acoustic stimuli. Here we examined the expression and localization of NB‐2 in the auditory brainstem during development in the rat. NB‐2 w...