Low-temperature enhances production of severe fever with thrombocytopenia syndrome virus virus-like particles - Loop, Isabelle; Ke, Yuan-Dun; Chen, Wei-June; Tsai, Kun-Hsien; Hsu, Wei-Li; Fan, Yi-Chin (Applied microbiology and biotechnology, 2025)
Keywords: Animals; Antigens; Antigens, Viral - genetics; Antigens, Viral - immunology; Assembly; Biomedical and Life Sciences; Biotechnological Products and Process Engineering; Biotechnology; Centrifugation; Chlorocebus aethiops; Cold Temperature; COS Cells; density gradient centrifugation; Epitopes; Epitopes - immunology; Fever; genotype; Genotypes; Glycoproteins; Glycoproteins - genetics; Glycoproteins - immunology; HEK293 Cells; Huaiyangshan banyangvirus; Humans; Life Sciences; Low temperature; Microbial Genetics and Genomics; Microbiology; monitoring; Monoclonal antibodies; nucleocapsid proteins; Nucleocapsids; Phlebovirus - genetics; Phlebovirus - immunology; plasmids; Proteins; RNA; Serology; severe fever with thrombocytopenia syndrome; Severe Fever with Thrombocytopenia Syndrome - virology; sucrose; Surveillance; Thrombocytopenia; Transmission electron microscopy; Vaccine development; Vaccines; Vaccines, Virus-Like Particle - immunology; Viral Proteins - genetics; virion; Virions; Virus-like particles; Viruses; Zoonoses; Genotype; Severe fever with thrombocytopenia syndrome virus; Virus-like particle; Low-temperature cultivation; Glycoprotein; Mammalian cells