Modulation of lung CD11b+ dendritic cells by acupuncture alleviates Th2 airway inflammation in allergic asthma

• Published in: Chinese medicine Vol. 20; no. 1; pp. 67 - 16
• Main Authors: Cheng, Mi, Shang, Pan-Pan, Wei, Dan-Dan, Long, Jie, Zhang, Xue, Wu, Quan-Long, Bassi, Gabriel Shimizu, Wang, Yu, Chen, Yan-Jiao, Yin, Lei-Miao, Yang, Yong-Qing, Xu, Yu-Dong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 22.05.2025; BioMed Central; BMC
• Subjects: Acupuncture; Adoptive transfer; Airway epithelium; Allergic asthma; Analysis; Antigens; Asthma; Bone marrow; CD11b antigen; CD86 antigen; Cell activation; Chemokines; Cytokines; Dendritic cells; Flow cytometry; Helper cells; Hyperplasia; Immune response; Immunoglobulin E; Infiltration; Inflammation; Laboratory animals; Lungs; Lymphocytes T; Lymphoid cells; Monocyte chemoattractant protein 1; Ox40L protein; Respiratory tract diseases; T cells; Th2 cell; Thymic stromal lymphopoietin; Traditional Chinese medicine; Type 2 innate lymphoid cells; North Carolina; Alarmin cytokines; Allergic asthma; Type 2 innate lymphoid cells; Dendritic cells; Immunoregulation; Th2 cell; Acupuncture; Airway epithelium

Allergic asthma features Th2-mediated airway inflammation, with dendritic cells (DCs) playing a crucial role. Acupuncture shows promise in modulating immune responses, yet its mechanisms in allergic asthma are not well understood. This study explores how acupuncture alleviates Th2 airway inflammatio...