The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria - Wang, Xiaoxin X.; Jiang, Tao; Shen, Yan; Adorini, Luciano; Pruzanski, Mark; Gonzalez, Frank J.; Scherzer, Pnina; Lewis, Linda; Miyazaki-Anzai, Shinobu; Levi, Moshe (American Journal of Physiology - Renal Physiology, 2009)
Keywords: Animals; Chenodeoxycholic Acid - analogs & derivatives; Chenodeoxycholic Acid - pharmacology; Diet; Diet - adverse effects; Extracellular Matrix Proteins - antagonists & inhibitors; Fatty Acids - antagonists & inhibitors; Fibrosis - etiology; Glomerular Mesangium - pathology; Inflammation Mediators - metabolism; Intercellular Signaling Peptides and Proteins - metabolism; Kidney - metabolism; Kidney - pathology; Kidney diseases; Kidney Glomerulus - pathology; Kidneys; Lipid Metabolism; Lipids; Male; Medical disorders; Metabolism; Mice; Mice, Inbred DBA; Mice, Knockout; Nephritis - etiology; Nephritis - pathology; Oxidative Stress - drug effects; Podocytes - pathology; Proteinuria - etiology; Proteinuria - physiopathology; Receptors, Cytoplasmic and Nuclear - drug effects; Receptors, Cytoplasmic and Nuclear - metabolism; Sterol Regulatory Element Binding Protein 1 - metabolism; Triglycerides - antagonists & inhibitors