Effect of several variables in the polymer toys additive migration to saliva

Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic toys to saliva was analyzed to protect children in their habits of sucking and biting. Most of target additives appear no-regulated in toys n...

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Published inTalanta (Oxford) Vol. 85; no. 4; pp. 2080 - 2088
Main Authors Noguerol-Cal, R., López-Vilariño, J.M., González-Rodríguez, M.V., Barral-Losada, L.
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 30.09.2011
Elsevier
Subjects
Additives
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Clinical Chemistry Tests - methods
Evaporative
Exact sciences and technology
Friction
Humans
Light scattering
Migration
Migration tests
Motion
Other chromatographic methods
Play and Playthings
Polymeric additives
Polymers - analysis
Polymers - chemistry
Polymers - isolation & purification
Polymers - toxicity
Saliva
Saliva - chemistry
Spectrometric and optical methods
Temperature
Time Factors
Toys
Ultrasonic testing
Migration tests
Toys
Polymeric additives
Human
Temperature
Dyes
Liquid liquid extraction
Toxicity
Light scattering
Polymer
Liquid chromatography
Time
Antioxidant
Chemical enrichment
Additive
Target
Amine
Ultraviolet detector
Dynamics
Detection limit
Performance analysis
Tool
Ultraviolet visible spectrometry
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Abstract Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic toys to saliva was analyzed to protect children in their habits of sucking and biting. Most of target additives appear no-regulated in toys normative but adverse effects on human health of some of them have been demonstrated and their presence in others commercial articles normative has been included. In order to offer an effective and easy tool to perform these controls, migration tests by dynamic and static contact, followed by a preconcentration step by liquid–liquid extraction (LLE) and ultra performance liquid chromatographic analysis with ultraviolet-visible and evaporative light scattering detections (UPLC-UV/Vis-ELSD) have been optimized to evaluate the migrated amounts of the additives in saliva simulant. The detection limits of the migration methodologies were ranged from 8.68×10−2 to 1.30×10−3mg migrated (Lsimulant)−1. Influence of several variables on this mass transport, as time, temperature and friction, was also analyzed to achieve the most aggressive methodology to protect consumers. Migration of several studied additives, whose presence has been demonstrated in several purchased commercial toys, has been observed.
AbstractList Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic toys to saliva was analyzed to protect children in their habits of sucking and biting. Most of target additives appear no-regulated in toys normative but adverse effects on human health of some of them have been demonstrated and their presence in others commercial articles normative has been included. In order to offer an effective and easy tool to perform these controls, migration tests by dynamic and static contact, followed by a preconcentration step by liquid-liquid extraction (LLE) and ultra performance liquid chromatographic analysis with ultraviolet-visible and evaporative light scattering detections (UPLC-UV/Vis-ELSD) have been optimized to evaluate the migrated amounts of the additives in saliva simulant. The detection limits of the migration methodologies were ranged from 8.68 x 10 super(-2) to 1.30 x 10 super(-3) mg migrated (L simulant) super(-1). Influence of several variables on this mass transport, as time, temperature and friction, was also analyzed to achieve the most aggressive methodology to protect consumers. Migration of several studied additives, whose presence has been demonstrated in several purchased commercial toys, has been observed.
Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic toys to saliva was analyzed to protect children in their habits of sucking and biting. Most of target additives appear no-regulated in toys normative but adverse effects on human health of some of them have been demonstrated and their presence in others commercial articles normative has been included. In order to offer an effective and easy tool to perform these controls, migration tests by dynamic and static contact, followed by a preconcentration step by liquid-liquid extraction (LLE) and ultra performance liquid chromatographic analysis with ultraviolet-visible and evaporative light scattering detections (UPLC-UV/Vis-ELSD) have been optimized to evaluate the migrated amounts of the additives in saliva simulant. The detection limits of the migration methodologies were ranged from 8.68 × 10(-2) to 1.30 × 10(-3)mg migrated (L simulant)(-1). Influence of several variables on this mass transport, as time, temperature and friction, was also analyzed to achieve the most aggressive methodology to protect consumers. Migration of several studied additives, whose presence has been demonstrated in several purchased commercial toys, has been observed.
Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic toys to saliva was analyzed to protect children in their habits of sucking and biting. Most of target additives appear no-regulated in toys normative but adverse effects on human health of some of them have been demonstrated and their presence in others commercial articles normative has been included. In order to offer an effective and easy tool to perform these controls, migration tests by dynamic and static contact, followed by a preconcentration step by liquid–liquid extraction (LLE) and ultra performance liquid chromatographic analysis with ultraviolet-visible and evaporative light scattering detections (UPLC-UV/Vis-ELSD) have been optimized to evaluate the migrated amounts of the additives in saliva simulant. The detection limits of the migration methodologies were ranged from 8.68×10−2 to 1.30×10−3mg migrated (Lsimulant)−1. Influence of several variables on this mass transport, as time, temperature and friction, was also analyzed to achieve the most aggressive methodology to protect consumers. Migration of several studied additives, whose presence has been demonstrated in several purchased commercial toys, has been observed.
Author Noguerol-Cal, R.
González-Rodríguez, M.V.
Barral-Losada, L.
López-Vilariño, J.M.
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Issue 4
Keywords Migration tests
Toys
Polymeric additives
Human
Temperature
Dyes
Liquid liquid extraction
Toxicity
Light scattering
Polymer
Liquid chromatography
Time
Antioxidant
Chemical enrichment
Additive
Target
Amine
Ultraviolet detector
Dynamics
Detection limit
Performance analysis
Tool
Ultraviolet visible spectrometry
Language English
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Snippet Capacity to migrate of a representative group of polymeric additives, dyes, antioxidants, hindered amine light stabilizers (HALS) or antistatics, from plastic...
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SubjectTerms Additives
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Clinical Chemistry Tests - methods
Evaporative
Exact sciences and technology
Friction
Humans
Light scattering
Migration
Migration tests
Motion
Other chromatographic methods
Play and Playthings
Polymeric additives
Polymers - analysis
Polymers - chemistry
Polymers - isolation & purification
Polymers - toxicity
Saliva
Saliva - chemistry
Spectrometric and optical methods
Temperature
Time Factors
Toys
Ultrasonic testing
Title Effect of several variables in the polymer toys additive migration to saliva
URI https://dx.doi.org/10.1016/j.talanta.2011.07.035
https://www.ncbi.nlm.nih.gov/pubmed/21872061
https://search.proquest.com/docview/885907756
https://search.proquest.com/docview/926290069
Volume 85
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