Mutations on COVID-19 diagnostic targets

• Published in: Genomics (San Diego, Calif.) Vol. 112; no. 6; pp. 5204 - 5213
• Main Authors: Wang, Rui, Hozumi, Yuta, Yin, Changchuan, Wei, Guo-Wei
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2020
• Subjects: Coronavirus Envelope Proteins - genetics; COVID-19 - virology; COVID-19 infection; COVID-19 Testing; DNA Primers; genes; genotyping; Genotyping Techniques; Humans; immune response; messenger RNA; Mutation; mutation rate; nucleocapsid; Original; pandemic; Polymorphism, Single Nucleotide; proteins; SARS-CoV-2 - genetics; SARS-CoV-2 - isolation & purification; Severe acute respiratory syndrome coronavirus 2; therapeutics; vaccines

Effective, sensitive, and reliable diagnostic reagents are of paramount importance for combating the ongoing coronavirus disease 2019 (COVID-19) pandemic when there is neither a preventive vaccine nor a specific drug available for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It will...