Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency - Dorman, Agnieszka; Bendoumou, Maryam; Valaitienė, Aurelija; Wadas, Jakub; Ali, Haider; Dutilleul, Antoine; Maiuri, Paolo; Nestola, Lorena; Bociaga-Jasik, Monika; Mchantaf, Gilbert; Necsoi, Coca; De Wit, Stéphane; et al. (Nature communications, 2025)
Keywords: 14/19; 14/35; 14/63; 38/1; 38/109; 38/32; 38/77; 38/88; 38/89; 38/90; 631/326/596/2557; 631/337/1645/2052; Active Transport, Cell Nucleus; Antiretroviral therapy; Biotechnology; Cell Nucleus - metabolism; Cell Nucleus - virology; DNA methylation; Epigenetics; Exosome Multienzyme Ribonuclease Complex - metabolism; Gene regulation; HEK293 Cells; HIV; HIV Infections - drug therapy; HIV Infections - virology; HIV-1 - genetics; HIV-1 - physiology; Human immunodeficiency virus; Humanities and Social Sciences; Humans; Latency; multidisciplinary; Post-transcription; Proteins; Retention; rev Gene Products, Human Immunodeficiency Virus - genetics; rev Gene Products, Human Immunodeficiency Virus - metabolism; Ribonucleic acid; RNA; RNA Helicases; RNA Processing, Post-Transcriptional; RNA Splicing; RNA transport; RNA, Viral - genetics; RNA, Viral - metabolism; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; Science; Science (multidisciplinary); Viral infections; Virology; Virus Activation; Virus Latency - genetics; Virus Replication