Femoral cartilage defects initiate from medial meniscus extrusion or tibial cartilage lesions and expand in knee osteoarthritis as revealed by 3D MRI analysis

• Published in: Scientific reports Vol. 14; no. 1; pp. 25937 - 12
• Main Authors: Katano, Hisako, Ozeki, Nobutake, Mizuno, Mitsuru, Endo, Kentaro, Koga, Hideyuki, Masumoto, Jun, Sekiya, Ichiro
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 29.10.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 3D MRI; 692/4023/1671/1354; 692/698/1671/1354; Adult; Aged; Cartilage; Cartilage (articular); Cartilage diseases; Cartilage, Articular - diagnostic imaging; Cartilage, Articular - pathology; Cross-Sectional Studies; Female; Femoral cartilage; Femur; Femur - diagnostic imaging; Femur - pathology; Humanities and Social Sciences; Humans; Imaging, Three-Dimensional - methods; Knee; Knee Joint - diagnostic imaging; Knee Joint - pathology; Lesions; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Medial meniscus extrusion; Menisci, Tibial - diagnostic imaging; Menisci, Tibial - pathology; Meniscus; Middle Aged; Morphology; multidisciplinary; Osteoarthritis; Osteoarthritis, Knee - diagnostic imaging; Osteoarthritis, Knee - pathology; Science; Science (multidisciplinary); Tibia - diagnostic imaging; Tibia - pathology; UMIN; UMIN000032826; Knee; 3D MRI; Medial meniscus extrusion; Femoral cartilage; Osteoarthritis

Knee osteoarthritis is characterized by articular cartilage wear, with its morphological progression not fully understood. This study aimed to elucidate factors contributing to femoral cartilage defects and their expansion in medial knee osteoarthritis, using a novel approach analyzing cross-section...