Germline sequence variation in cancer genes in Rwandan breast and prostate cancer cases

• Published in: Npj genomic medicine Vol. 9; no. 1; pp. 61 - 10
• Main Authors: Manirakiza, Achille VC, Baichoo, Shakuntala, Uwineza, Annette, Dukundane, Damas, Uwinkindi, Francois, Ngendahayo, Edouard, Rubagumya, Fidel, Muhawenimana, Emmanuel, Nsabimana, Nicaise, Nzeyimana, Innocent, Maniragaba, Theoneste, Ntirenganya, Faustin, Rurangwa, Ephrem, Mugenzi, Pacifique, Mutamuliza, Janviere, Runanira, Daniel, Niyibizi, Brandon A., Rugengamanzi, Eulade, Besada, Jeffrey, Nielsen, Sarah M., Bucknor, Brianna, Nussbaum, Robert L., Koeller, Diane, Andrews, Caroline, Mutesa, Leon, Fadelu, Temidayo, Rebbeck, Timothy R.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.11.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208/68; 692/4017; Age; Bioinformatics; Biomedical and Life Sciences; Biomedicine; BRCA2 protein; Breast; Breast cancer; Disease management; Females; Gene Function; Gene Therapy; Genes; Genetic counseling; Genetic diversity; Genetic screening; Genetic testing; Genetics; Health sciences; Human Genetics; Internal Medicine; Males; Medicine; Mutation; Patients; Prostate cancer; Teaching hospitals

Cancer genetic data from Sub-Saharan African (SSA) are limited. Patients with female breast (fBC), male breast (mBC), and prostate cancer (PC) in Rwanda underwent germline genetic testing and counseling. Demographic and disease-specific information was collected. A multi-cancer gene panel was used t...