Novel fibrin functionalized multilayered electrospun nanofiber membrane for burn wound treatment

• Published in: Journal of materials science Vol. 56; no. 22; pp. 12814 - 12834
• Main Authors: Talukder, Md Eman, Hasan, K. M. Faridul, Wang, Jianming, Yao, Jingbo, Li, Caolong, Song, Hongchen
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2021; Springer; Springer Nature B.V
• Subjects: alcohols; Antibacterial agents; antibacterial properties; Burns and scalds; Characterization and Evaluation of Materials; Chemistry and Materials Science; Chitosan; Classical Mechanics; crystal structure; Crystallography and Scattering Methods; Differential scanning calorimetry; drugs; E coli; Electrospinning; energy-dispersive X-ray analysis; Escherichia coli; Exudation; Fibrin; Fourier transform infrared spectroscopy; Fourier transforms; Gelatin; hydrophilicity; Infrared spectroscopy; Materials for Life Sciences; Materials Science; Membranes; Morphology; Nanocomposites; Nanofibers; Polymer Sciences; Polyvinyl alcohol; Regeneration; Skin; Sodium alginate; Solid Mechanics; Spectrum analysis; Stability analysis; Staphylococcus aureus; Thermal stability; Thermogravimetric analysis; thermogravimetry; Wound healing; X-ray diffraction; X-ray spectroscopy

In this study, a novel hybrid multilayered electrospun nanocomposite membrane (MENM) was developed for activated wound dressing applications. An established electrospinning process was employed to fabricate a tri-layer nanocomposite membrane where the lower layer was composed of chitosan (CS)/polyvi...