Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice - Halfmann, Peter J.; Patel, Raj S.; Loeffler, Kathryn; Yasuhara, Atsuhiro; Van De Velde, Lee-Ann; Yang, Jie E.; Chervin, Jordan; Troxell, Chloe; Huang, Min; Zheng, Naiying; Wright, Elizabeth R.; Thomas, Paul G.; et al. (Nature communications, 2025)
Keywords: 631/250/255/2514; 631/250/590/2294; 631/326/596/4130; 692/699/255/2514; 82/80; Animals; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Coronaviruses; COVID-19; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 - virology; COVID-19 Vaccines - immunology; Fc receptors; Female; Females; Humanities and Social Sciences; Humans; Mice; Mice, Knockout; Mice, Transgenic; multidisciplinary; Nanoparticles; Pandemics; Receptors, IgG - genetics; Receptors, IgG - immunology; Sarbecovirus; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Transgenic mice; Vaccines; Vaccines, Subunit - immunology; Viral diseases