Association of citrullination with the progression of aortic stenosis

• Published in: Scientific reports Vol. 13; no. 1; p. 8919
• Main Authors: Kim, Ah-Ram, Ji, Eunhye, Lee, Sahmin, Hong, Seokchan, Kim, Dae-Hee, Song, Jong-Min, Kang, Duk-Hyun, Song, Jae-Kwan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4019/592; 692/4019/592/75/591; Antibodies; Aortic stenosis; Aortic valve; Citrulline; Degeneration; Echocardiography; Humanities and Social Sciences; Immunohistochemistry; multidisciplinary; Science; Science (multidisciplinary); Western blotting

Despite its clinical importance, biomarkers of disease activity in aortic stenosis (AS) are lacking. We investigated the association between anti-cyclic citrullinated peptide (CCP) antibodies and AS. All 678 patients who underwent echocardiography and anti-CCP antibody testing were analysed. Anti-CC...