Collagen interactions: Drug design and delivery

• Published in: Advanced drug delivery reviews Vol. 97; pp. 69 - 84
• Main Authors: An, Bo, Lin, Yu-Shan, Brodsky, Barbara
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2016
• Subjects: Animals; Binding Sites; Collagen; Collagen - chemistry; Collagen - metabolism; Drug delivery; Drug Delivery Systems; Drug Design; Extracellular matrix; Humans; Interaction; Peptide; Recombinant collagen; Targeting; Triple helix; Recombinant collagen; Targeting; Collagen; Triple helix; Interaction; Extracellular matrix; Drug delivery; Peptide

Collagen is a major component in a wide range of drug delivery systems and biomaterial applications. Its basic physical and structural properties, together with its low immunogenicity and natural turnover, are keys to its biocompatibility and effectiveness. In addition to its material properties, th...