Impact of SARS-CoV-2 infection on respiratory and gut microbiome stability: a metagenomic investigation in long-term-hospitalized COVID-19 patients

• Published in: NPJ biofilms and microbiomes Vol. 10; no. 1; pp. 126 - 11
• Main Authors: Li, Zhengtu, Chen, Jing, Li, Yinhu, Li, Linghua, Zhan, Yangqing, Yang, Jiasheng, Wu, Huiqin, Li, Shaoqiang, Mo, Xiaoneng, Wang, Xidong, Mi, Yiqun, Zhou, Xi, Li, Yongming, Wang, Jun, Li, Yuanxiang, Sun, Ruilin, Cai, Weiping, Ye, Feng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.11.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326/2521; 631/326/2565/855; Adult; Aged; Bacteria - classification; Bacteria - genetics; Bacteria - isolation & purification; Biomedical and Life Sciences; Comparative analysis; Coronaviruses; COVID-19; COVID-19 - microbiology; COVID-19 - virology; Feces - microbiology; Feces - virology; Female; Gastrointestinal Microbiome - genetics; Gut microbiota; High-Throughput Nucleotide Sequencing; Hospitalization; Humans; Infections; Infectious diseases; Intestinal microflora; Intestine; Life Sciences; Male; Medical Microbiology; Metagenome; Metagenomics; Metagenomics - methods; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Microbiomes; Microorganisms; Middle Aged; Next-generation sequencing; Respiratory System - microbiology; Respiratory System - virology; SARS-CoV-2 - genetics; Severe acute respiratory syndrome coronavirus 2; Sputum; Sputum - microbiology; Sputum - virology

During the coronavirus disease 2019 (COVID-19) pandemic, the exploration of microecology has been essential for elucidating the intricacies of infection mechanisms and the recovery of afflicted individuals. To decipher the interplay of microorganisms between the intestinal and respiratory tracts, we...