Dried blood spots for monitoring and individualization of antiepileptic drug treatment

• Published in: European journal of pharmaceutical sciences Vol. 75; pp. 25 - 39
• Main Authors: Milosheska, Daniela, Grabnar, Iztok, Vovk, Tomaž
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.07.2015
• Subjects: Anticonvulsants - blood; Anticonvulsants - therapeutic use; Antiepileptic drugs; Clinical validation; Dried blood spots; Drug Monitoring - methods; Epilepsy - drug therapy; Humans; Reproducibility of Results; Therapeutic drug monitoring; Therapeutic drug monitoring; Clinical validation; Dried blood spots; Antiepileptic drugs

[Display omitted] Therapeutic drug monitoring (TDM) is a multi-disciplinary clinical specialty used for optimization and individualization of drug therapy in the general and special populations. Since most antiepileptic drugs (AEDs) are characterized by pronounced intra- and inter-individual variabi...