Multisite longitudinal reliability of tract-based spatial statistics in diffusion tensor imaging of healthy elderly subjects

• Published in: NeuroImage (Orlando, Fla.) Vol. 101; pp. 390 - 403
• Main Authors: Jovicich, Jorge, Marizzoni, Moira, Bosch, Beatriz, Bartrés-Faz, David, Arnold, Jennifer, Benninghoff, Jens, Wiltfang, Jens, Roccatagliata, Luca, Picco, Agnese, Nobili, Flavio, Blin, Oliver, Bombois, Stephanie, Lopes, Renaud, Bordet, Régis, Chanoine, Valérie, Ranjeva, Jean-Philippe, Didic, Mira, Gros-Dagnac, Hélène, Payoux, Pierre, Zoccatelli, Giada, Alessandrini, Franco, Beltramello, Alberto, Bargalló, Núria, Ferretti, Antonio, Caulo, Massimo, Aiello, Marco, Ragucci, Monica, Soricelli, Andrea, Salvadori, Nicola, Tarducci, Roberto, Floridi, Piero, Tsolaki, Magda, Constantinidis, Manos, Drevelegas, Antonios, Rossini, Paolo Maria, Marra, Camillo, Otto, Josephin, Reiss-Zimmermann, Martin, Hoffmann, Karl-Titus, Galluzzi, Samantha, Frisoni, Giovanni B.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2014; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Alzheimer's disease; Automation; Brain; Brain diffusion tensor imaging; Diffusion; Diffusion Tensor Imaging - instrumentation; Diffusion Tensor Imaging - methods; Diffusion Tensor Imaging - standards; Female; Humans; Longitudinal Studies; Male; Middle Aged; Multi-center; Multi-site MRI; Reliability; Reproducibility; Reproducibility of Results; Statistics; Studies; Tract-based spatial statistics; White Matter - anatomy & histology; Multi-center; Multi-site MRI; Brain diffusion tensor imaging; Reliability; Reproducibility; Tract-based spatial statistics

Large-scale longitudinal neuroimaging studies with diffusion imaging techniques are necessary to test and validate models of white matter neurophysiological processes that change in time, both in healthy and diseased brains. The predictive power of such longitudinal models will always be limited by...