Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles

• Published in: Nature communications Vol. 15; no. 1; pp. 7112 - 12
• Main Authors: Jeong, Yong Dam, Hart, William S., Thompson, Robin N., Ishikane, Masahiro, Nishiyama, Takara, Park, Hyeongki, Iwamoto, Noriko, Sakurai, Ayana, Suzuki, Michiyo, Aihara, Kazuyuki, Watashi, Koichi, Op de Coul, Eline, Ohmagari, Norio, Wallinga, Jacco, Iwami, Shingo, Miura, Fuminari
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.08.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114/2397; 692/699/255/2514; 692/700/478/174; COVID-19 - epidemiology; COVID-19 - prevention & control; COVID-19 - transmission; COVID-19 - virology; Disease Outbreaks - prevention & control; Effectiveness; Humanities and Social Sciences; Humans; Mpox; multidisciplinary; Outbreaks; Patient Isolation - methods; SARS-CoV-2 - isolation & purification; Science; Science (multidisciplinary); Viral diseases; Viral Load; Virus Shedding

The global outbreak of mpox in 2022 and subsequent sporadic outbreaks in 2023 highlighted the importance of nonpharmaceutical interventions such as case isolation. Individual variations in viral shedding dynamics may lead to either premature ending of isolation for infectious individuals, or unneces...