A computational fluid dynamics study to assess the impact of coughing on cerebrospinal fluid dynamics in Chiari type 1 malformation

• Published in: Scientific reports Vol. 14; no. 1; pp. 12717 - 15
• Main Authors: Vandenbulcke, Sarah, Condron, Paul, Safaei, Soroush, Holdsworth, Samantha, Degroote, Joris, Segers, Patrick
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.06.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114/2397; 639/766/189; 692/617/375; Arnold-Chiari Malformation - cerebrospinal fluid; Arnold-Chiari Malformation - complications; Arnold-Chiari Malformation - physiopathology; Brain; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure - physiology; Computational neuroscience; Computer Simulation; Cough; Cough - physiopathology; Female; Fluid dynamics; Humanities and Social Sciences; Humans; Hydrodynamics; multidisciplinary; Science; Science (multidisciplinary); Spinal cord; Spinal Cord - physiopathology; Ventricle (lateral)

Chiari type 1 malformation is a neurological disorder characterized by an obstruction of the cerebrospinal fluid (CSF) circulation between the brain (intracranial) and spinal cord (spinal) compartments. Actions such as coughing might evoke spinal cord complications in patients with Chiari type 1 mal...