Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior - Chourbaji, Sabine; Hellweg, Rainer; Brandis, Dorothee; Zörner, Björn; Zacher, Christiane; Lang, Undine E.; Henn, Fritz A.; Hörtnagl, Heide; Gass, Peter (Brain research. Molecular brain research., 2004)
Keywords: Adrenocorticotropic Hormone - blood; Adult and adolescent clinical studies; Analysis of Variance; Animals; Anxiety; BDNF; Behavior; Biogenic Monoamines - metabolism; Biological and medical sciences; Brain - anatomy & histology; Brain - enzymology; Brain - metabolism; Brain Chemistry; Brain-Derived Neurotrophic Factor - genetics; Brain-Derived Neurotrophic Factor - metabolism; Choline O-Acetyltransferase - metabolism; Chromatography, High Pressure Liquid - methods; Conditioning, Classical - physiology; Depression; Electrochemistry - methods; Enzyme-Linked Immunosorbent Assay - methods; Exploratory Behavior - physiology; Fear - physiology; Fundamental and applied biological sciences. Psychology; HPA system; Male; Maze Learning - physiology; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoamines; Mood disorders; Motor Activity - physiology; Nerve Growth Factor - analysis; Neurotrophins; Psychology. Psychoanalysis. Psychiatry; Psychomotor Performance - physiology; Psychopathology. Psychiatry; Reaction Time; Stress, Physiological; Vertebrates: nervous system and sense organs; Disorders of the nervous system; BDNF; Depression; Mice; Behavior; HPA system; Neurotrophins; Monoamines; Mood disorder; Neurotrophin; Acyltransferases; Enzyme; Transferases; Rodentia; Central nervous system; Choline O-acetyltransferase; Encephalon; Vertebrata; Mammalia; Mouse; Animal; Brain derived neurotrophic factor; Monoamines: Mice