Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections

• Published in: Bone Research Vol. 12; no. 1; p. 28
• Main Authors: Qin, Leilei, Yang, Shuhao, Zhao, Chen, Yang, Jianye, Li, Feilong, Xu, Zhenghao, Yang, Yaji, Zhou, Haotian, Li, Kainan, Xiong, Chengdong, Huang, Wei, Hu, Ning, Hu, Xulin
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.05.2024; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/443/63; 631/443/811; Animals; Bone Regeneration; Drug resistance; Humans; Infections; Internal Medicine; Medicine; Medicine & Public Health; Orthopedics; Osteomyelitis - drug therapy; Osteomyelitis - microbiology; Osteomyelitis - therapy; Review; Review Article; Tissue engineering; Tissue Engineering - methods

Osteomyelitis is a devastating disease caused by microbial infection in deep bone tissue. Its high recurrence rate and impaired restoration of bone deficiencies are major challenges in treatment. Microbes have evolved numerous mechanisms to effectively evade host intrinsic and adaptive immune attack...