Characterization of recombinant rabies virus carrying double glycoprotein genes

• Published in: Microbiology and immunology Vol. 50; no. 3; p. 187
• Main Authors: Hosokawa-Muto, Junji, Ito, Naoto, Yamada, Kentaro, Shimizu, Kenta, Sugiyama, Makoto, Minamoto, Nobuyuki
• Format: Journal Article
• Language: English
• Published: Australia 01.01.2006
• Subjects: Animals; Antigens, Viral - genetics; Cell Line, Tumor; Female; Glycoproteins - genetics; Immunization; Mice; Rabies - prevention & control; Rabies - virology; Rabies Vaccines - administration & dosage; Rabies Vaccines - genetics; Rabies virus - genetics; Rabies virus - growth & development; Rabies virus - pathogenicity; Recombination, Genetic; Vaccines, Inactivated - administration & dosage; Vaccines, Inactivated - genetics; Viral Envelope Proteins - genetics; Virulence

A recombinant rabies virus carrying double glycoprotein (G) genes, R(NPMGGL) strain, was generated by a reverse genetics system utilizing cloned cDNA of the RC-HL strain, and the biological properties of the virus were compared to those of the recombinant RC-HL (rRC-HL) strain. The extents of virus...