N‐glycosylation of the SARS‐CoV‐2 spike protein at Asn331 and Asn343 is involved in spike‐ACE2 binding, virus entry, and regulation of IL‐6 - Das, Tuhin; Luo, Shuhong; Tang, Hao; Fang, Jianmin; Mao, Yinging; Yen, Haw‐Han; Dash, Sabyasachi; Shajahan, Asif; Pepi, Lauren; Huang, Steven; Jones, Valerie S.; Xie, Shehuo; et al. (Microbiology and immunology, 2024)
Keywords: ACE2; Angiotensin-Converting Enzyme 2 - metabolism; Asparagine - metabolism; COVID-19 - metabolism; COVID-19 - virology; COVID‐19; Glycosylation; HEK293 Cells; Humans; IL‐6; Interleukin-6 - metabolism; N‐glycosylation; Polysaccharides - metabolism; Protein Binding; receptor‐binding domain; SARS-CoV-2 - metabolism; SARS-CoV-2 - physiology; SARS‐CoV‐2; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - metabolism; spike protein; Virus Internalization; ACE2; COVID‐19; SARS‐CoV‐2; receptor‐binding domain; spike protein; N‐glycosylation; IL‐6