Red Blood Cell Survival in Long-term Dialysis Patients

• Published in: American journal of kidney diseases Vol. 58; no. 4; pp. 591 - 598
• Main Authors: Vos, Frederiek E., Schollum, John B., Coulter, Carolyn V., Doyle, Terrence C.A., Duffull, Stephen B., Walker, Robert J.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.10.2011; Elsevier
• Subjects: Adult; Aged; anemia; Anemia - blood; Anemia - drug therapy; Anemia - epidemiology; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Arteriolosclerosis - blood; Arteriolosclerosis - complications; Biological and medical sciences; Case-Control Studies; Chromium Radioisotopes - blood; chronic kidney disease; Emergency and intensive care: renal failure. Dialysis management; Erythrocyte Aging; Female; Hematinics - therapeutic use; hemodialysis; Hemoglobins - analysis; Humans; Intensive care medicine; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - etiology; Kidney Failure, Chronic - therapy; Kidneys; Male; Medical sciences; Middle Aged; Nephrology; Nephrology. Urinary tract diseases; New Zealand; Peritoneal Dialysis; Polycystic Kidney Diseases - blood; Polycystic Kidney Diseases - complications; Red blood cell survival; Renal Dialysis; uremia; Urinary system involvement in other diseases. Miscellaneous; New Zealand; uremia; hemodialysis; chronic kidney disease; peritoneal dialysis; Red blood cell survival; anemia; Kidney disease; Human; Nephrology; Urinary system disease; Anemia; Hemodialysis; Red blood cell; Hemopathy; Chronic kidney disease; Long term; Survival; Peritoneal dialysis; Urology; Extrarenal dialysis; Blood cell; Renal failure; Uremia

Shortening of red blood cell (RBC) survival contributes to the anemia of chronic kidney disease. The toxic uremic environment accounts for the decreased RBC life span. The contribution of mechanical damage caused by hemodialysis to the shortened life span is unclear. Reductions up to 70% in RBC surv...