Environmental control of cell size at division

• Published in: Current opinion in cell biology Vol. 24; no. 6; pp. 838 - 844
• Main Authors: Davie, Elizabeth, Petersen, Janni
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2012
• Subjects: Cell Division; cell growth; Cell Size; Internal Medicine; Mechanistic Target of Rapamycin Complex 1; mitosis; Multiprotein Complexes - metabolism; nutrient availability; nutrients; physiology; Signal Transduction; TOR Serine-Threonine Kinases - metabolism

Tight coupling between cell growth and cell cycle progression allows cells to adjust their size to the demands of proliferation in varying nutrient environments. Target of rapamycin (TOR) signalling pathways co-ordinate cell growth with cell cycle progression in response to altered nutritional avail...