Immunohistological Analysis of ABCD3 Expression in Caucasian and African American Prostate Tumors

• Published in: BioMed research international Vol. 2015; no. 2015; pp. 1 - 6
• Main Authors: Soliman, Karam F. A., Hernandez, Brenda Y., Chan, Owen T. M., Jones-Triche, Jacqueline, Reams, Romonia Renee, Yates, Clayton
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2015; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: African Americans; Aged; Aggressiveness; ATP-Binding Cassette Transporters - metabolism; Biological markers; Black or African American; Black People; Case-Control Studies; Humans; Male; Medical research; Men; Neoplasm Grading; Physiological aspects; Prostate - metabolism; Prostate - pathology; Prostate cancer; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; Tumors; White People; United States > US

In a previously published study, we showed that expression of the ABCD3 gene increased with increasing metastatic potential in a panel of prostate cancer cell lines derived from African American and Caucasian American men. Given importance of identifying biomarker(s) that can distinguish indolent ve...