The influence of Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp. shermanii JS on potentially carcinogenic bacterial activity in human colon

• Published in: International journal of food microbiology Vol. 128; no. 2; pp. 406 - 410
• Main Authors: Hatakka, Katja, Holma, Reetta, El-Nezami, Hani, Suomalainen, Tarja, Kuisma, Minna, Saxelin, Maija, Poussa, Tuija, Mykkänen, Hannu, Korpela, Riitta
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 10.12.2008; [Amsterdam; New York, NY]: Elsevier Science; Elsevier
• Subjects: administration & dosage; Adult; antagonists & inhibitors; anticarcinogenic activity; Bacteria; beta-glucosidase; beta-Glucosidase - antagonists & inhibitors; beta-Glucosidase - metabolism; beta-glucuronidase; Biological and medical sciences; carcinogenesis; Colon; Colon - enzymology; Colon - microbiology; Colonic Neoplasms; Colonic Neoplasms - enzymology; Colonic Neoplasms - microbiology; Colonic Neoplasms - prevention & control; Colony Count, Microbial; colorectal neoplasms; Cross-Over Studies; Double-Blind Method; enzyme activity; enzymology; feces; Feces - enzymology; Feces - microbiology; Food industries; Food microbiology; Fundamental and applied biological sciences. Psychology; Glucuronidase; Glucuronidase - antagonists & inhibitors; Glucuronidase - metabolism; Humans; intestinal microorganisms; lactic acid bacteria; Lacticaseibacillus rhamnosus; Lactobacillus; Lactobacillus rhamnosus; Lactobacillus rhamnosus - physiology; Lactobacillus rhamnosus LC705; Male; men; metabolism; microbiology; Middle Aged; physiology; plate count; prevention & control; Probiotics; Probiotics - administration & dosage; Propionibacterium; Propionibacterium - physiology; Propionibacterium freudenreichii; Propionibacterium freudenreichii ssp. shermanii JS; temporal variation; Urease; Urease - antagonists & inhibitors; Urease - metabolism; Young Adult; β-glucosidase; β-glucuronidase; Probiotics; β-glucuronidase; Urease; β-glucosidase; Propionibacterium freudenreichii ssp. shermanii JS; Lactobacillus rhamnosus LC705; Human; Probiotic; Lactic acid bacteria; β-Glucuronidase; Digestive system; Enzyme; Gut; Propionibacterium freudenreichii; Glycosylases; Glycosidases; Propionibacteriaceae; Bacteria; Hydrolases; Lactobacillaceae; Actinomycetes; Colon; Lactobacillus

The bacterial enzymes β-glucosidase, β-glucuronidase, and urease may contribute to the development of colon cancer by generating carcinogens. A reduction in the activity of these enzymes by certain lactic acid bacteria is considered to be beneficial. This study examined fecal β-glucosidase, β-glucur...