Association of body burden of mercury with liver function test status in the U.S. population

• Published in: Environment international Vol. 70; pp. 88 - 94
• Main Authors: Lin, Yu-Sheng, Ginsberg, Gary, Caffrey, James L., Xue, Jianping, Vulimiri, Suryanarayana V., Nath, Raghu G., Sonawane, Babasaheb
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.09.2014; Elsevier
• Subjects: Adult; adults; Aged; alanine transaminase; Alanine Transaminase - blood; Animals; Aspartate Aminotransferases - blood; aspartate transaminase; Biological and medical sciences; biotransformation; Blood; blood serum; Body Burden; Chemical and industrial products toxicology. Toxic occupational diseases; Environment. Living conditions; Environmental Exposure; Environmental pollutants toxicology; enzyme activity; excretion; feces; Female; fish consumption; gamma-glutamyltransferase; gamma-Glutamyltransferase - blood; gender; Humans; Life Style; lifestyle; Liver; Liver - enzymology; Liver - metabolism; liver function; Liver Function Tests; Male; Medical sciences; Mercury; Mercury - blood; Mercury - urine; Metals and various inorganic compounds; Methyl mercury; methylmercury compounds; Methylmercury Compounds - blood; Middle Aged; National Health and Nutrition Examination Survey; Nutrition Surveys; pharmacokinetics; Population Surveillance; prospective studies; Public health. Hygiene; Public health. Hygiene-occupational medicine; regression analysis; Toxicokinetics; Toxicology; United States; urinalysis; Urine; Young Adult; United States; Urine; Toxicokinetics; Mercury; Methyl mercury; Liver; Blood; Human; Biological fluid; Toxicity; Epidemiology; Heavy metal; Concentration measurement; Liver function; Population

The majority of mercury (Hg) exposure in the US population is from consumption of fish contaminated with methylmercury (MeHg). Since inorganic Hg is the predominant form excreted in the feces and urine, hepatic biotransformation is a critical step in its normal clearance. This study was set to test...