Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges

Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will require targeted interventions within the justice system effective at providing diagnosis and treatment. We implemented a novel HCV screenin...

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Published inThe International journal of drug policy Vol. 103; p. 103668
Main Authors Jacka, Brendan P, Bazerman, Laurie B, Dickerson, Collin, Moody, Marc, Martin, Johanna, Patry, Emily, Cady, Treniece, Compere, Hacheming, Boudreau, Matthew, Beckwith, Curt G
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.05.2022
Elsevier Science Ltd
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Abstract Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will require targeted interventions within the justice system effective at providing diagnosis and treatment. We implemented a novel HCV screening and treatment intervention for persons under community supervision in Rhode Island, USA during April 2018––March 2020. Participants received rapid point-of-care HCV antibody testing onsite and referral to community laboratory and treatment services as indicated. We assessed the HCV care cascade to identify areas for improvement. Overall, 483 individuals were screened for HCV antibody; 85 (18%) were positive. A minority of participants with positive HCV antibody tests (n=25/85, 29%) presented to community laboratories for confirmatory testing. Among participants that received HCV viral load results and linked to a treatment provider (n=12), four initiated treatment, three had record of completing treatment, and two were confirmed to have achieved cure. Linkage to HCV viral load testing and treatment was challenging in this community supervision population, with substantial loss to follow-up at each step of the HCV cascade. Community supervision remains an important venue for case identification but substantial barriers to accessing HCV treatment exist. Innovative HCV diagnosis and treatment strategies are needed for community supervision populations.
AbstractList Background: Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will require targeted interventions within the justice system effective at providing diagnosis and treatment. Methods: We implemented a novel HCV screening and treatment intervention for persons under community supervision in Rhode Island, USA during April 2018––March 2020. Participants received rapid point-of-care HCV antibody testing onsite and referral to community laboratory and treatment services as indicated. We assessed the HCV care cascade to identify areas for improvement. Results: Overall, 483 individuals were screened for HCV antibody; 85 (18%) were positive. A minority of participants with positive HCV antibody tests (n=25/85, 29%) presented to community laboratories for confirmatory testing. Among participants that received HCV viral load results and linked to a treatment provider (n=12), four initiated treatment, three had record of completing treatment, and two were confirmed to have achieved cure. Conclusion: Linkage to HCV viral load testing and treatment was challenging in this community supervision population, with substantial loss to follow-up at each step of the HCV cascade. Community supervision remains an important venue for case identification but substantial barriers to accessing HCV treatment exist. Innovative HCV diagnosis and treatment strategies are needed for community supervision populations.
Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will require targeted interventions within the justice system effective at providing diagnosis and treatment. We implemented a novel HCV screening and treatment intervention for persons under community supervision in Rhode Island, USA during April 2018--March 2020. Participants received rapid point-of-care HCV antibody testing onsite and referral to community laboratory and treatment services as indicated. We assessed the HCV care cascade to identify areas for improvement. Overall, 483 individuals were screened for HCV antibody; 85 (18%) were positive. A minority of participants with positive HCV antibody tests (n=25/85, 29%) presented to community laboratories for confirmatory testing. Among participants that received HCV viral load results and linked to a treatment provider (n=12), four initiated treatment, three had record of completing treatment, and two were confirmed to have achieved cure. Linkage to HCV viral load testing and treatment was challenging in this community supervision population, with substantial loss to follow-up at each step of the HCV cascade. Community supervision remains an important venue for case identification but substantial barriers to accessing HCV treatment exist. Innovative HCV diagnosis and treatment strategies are needed for community supervision populations.
BACKGROUNDPersons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will require targeted interventions within the justice system effective at providing diagnosis and treatment. METHODSWe implemented a novel HCV screening and treatment intervention for persons under community supervision in Rhode Island, USA during April 2018--March 2020. Participants received rapid point-of-care HCV antibody testing onsite and referral to community laboratory and treatment services as indicated. We assessed the HCV care cascade to identify areas for improvement. RESULTSOverall, 483 individuals were screened for HCV antibody; 85 (18%) were positive. A minority of participants with positive HCV antibody tests (n=25/85, 29%) presented to community laboratories for confirmatory testing. Among participants that received HCV viral load results and linked to a treatment provider (n=12), four initiated treatment, three had record of completing treatment, and two were confirmed to have achieved cure. CONCLUSIONLinkage to HCV viral load testing and treatment was challenging in this community supervision population, with substantial loss to follow-up at each step of the HCV cascade. Community supervision remains an important venue for case identification but substantial barriers to accessing HCV treatment exist. Innovative HCV diagnosis and treatment strategies are needed for community supervision populations.
ArticleNumber 103668
Author Beckwith, Curt G
Cady, Treniece
Jacka, Brendan P
Dickerson, Collin
Bazerman, Laurie B
Martin, Johanna
Patry, Emily
Moody, Marc
Boudreau, Matthew
Compere, Hacheming
AuthorAffiliation 4 Rhode Island Department of Corrections, Pawtucket, Rhode Island, USA
3 The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA
1 Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA
2 Division of Infectious Diseases, The Miriam Hospital, Providence, Rhode Island, USA
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Keywords Care cascade
healthcare access
HCV elimination
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Snippet Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to eliminate HCV will...
Background: Persons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to...
BACKGROUNDPersons involved with the justice system have an elevated risk of hepatitis C virus (HCV) yet remain marginalized from treatment. Efforts to...
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StartPage 103668
SubjectTerms Antibodies
Care cascade
Community
Cure
Diagnostic tests
Drug policy
Feasibility
Feasibility Studies
HCV elimination
healthcare access
Hepacivirus
Hepatitis
Hepatitis C
Hepatitis C - diagnosis
Hepatitis C - epidemiology
Hepatitis C Antibodies
Humans
Intervention
Justice
Laboratories
Mass Screening - methods
Medical diagnosis
Medical screening
Supervision
Title Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges
URI https://dx.doi.org/10.1016/j.drugpo.2022.103668
https://www.ncbi.nlm.nih.gov/pubmed/35367903
https://www.proquest.com/docview/2672046694
https://search.proquest.com/docview/2646941662
https://pubmed.ncbi.nlm.nih.gov/PMC9070602
Volume 103
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