Development and Arealization of the Cerebral Cortex

• Published in: Neuron (Cambridge, Mass.) Vol. 103; no. 6; pp. 980 - 1004
• Main Authors: Cadwell, Cathryn R., Bhaduri, Aparna, Mostajo-Radji, Mohammed A., Keefe, Matthew G., Nowakowski, Tomasz J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 25.09.2019; Elsevier Limited
• Subjects: Animals; autism; brain development; Cerebral cortex; Cerebral Cortex - embryology; Cognitive ability; Deep Learning; Gene expression; Gene Expression Regulation, Developmental; Genotype & phenotype; Homology; human brain; Humans; Interneurons - cytology; Interneurons - metabolism; machine learning; Neural Inhibition; Neural networks; Neurodevelopmental disorders; neurogenesis; Neurogenesis - genetics; Neurogenesis - physiology; Neurons; Neurons - cytology; Neurons - metabolism; protocortex; protomap; serial homology; Single-Cell Analysis; Thalamus - embryology; brain development; cerebral cortex; human brain; protocortex; neural networks; neurogenesis; machine learning; autism; protomap; serial homology

Adult cortical areas consist of specialized cell types and circuits that support unique higher-order cognitive functions. How this regional diversity develops from an initially uniform neuroepithelium has been the subject of decades of seminal research, and emerging technologies, including single-ce...