Chemokines and the immune response to cancer

• Published in: Immunity (Cambridge, Mass.) Vol. 54; no. 5; pp. 859 - 874
• Main Authors: Ozga, Aleksandra J., Chow, Melvyn T., Luster, Andrew D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 11.05.2021; Elsevier Limited
• Subjects: Animals; Anticancer properties; Bone marrow; Cancer; Cancer therapies; Carcinogenesis - immunology; Cell migration; Cell Movement - immunology; Chemokines; Chemokines - immunology; Cytokines; Genotype & phenotype; Humans; Immune response; Immune system; Immunity - immunology; Immunotherapy; Ligands; Localization; Lymphocytes; Neoplasms - immunology; Regulation; Tumor microenvironment; Tumor Microenvironment - immunology; Tumorigenesis; Tumors

Chemokines are chemotactic cytokines that regulate the migration of immune cells. Chemokines function as cues for the coordinated recruitment of immune cells into and out of tissue and also guide the spatial organization and cellular interactions of immune cells within tissues. Chemokines are critic...