T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation - Tu, Eric; Chia, Cheryl P.Z.; Chen, Weiwei; Zhang, Dunfang; Park, Sang A.; Jin, Wenwen; Wang, Dandan; Alegre, Maria-Luisa; Zhang, Ying E.; Sun, Lingyun; Chen, WanJun (Immunity (Cambridge, Mass.), 2018)
Keywords: Animals; Antigens; Autoantigens; Autoimmunity; Autoimmunity - immunology; CARD Signaling Adaptor Proteins - genetics; CARD Signaling Adaptor Proteins - metabolism; CARD11; Caspase; CD4-Positive T-Lymphocytes - immunology; Cell activation; Cell Line; Cell Proliferation; Colitis - immunology; Colitis - pathology; Disease Models, Animal; Down-Regulation - immunology; Experiments; Guanylate Cyclase - genetics; Guanylate Cyclase - metabolism; HEK293 Cells; Humans; IL-6; Interleukin 6; Interleukin-6 - immunology; Lupus Erythematosus, Systemic - immunology; Lymphocyte Activation - immunology; Lymphocytes; Lymphocytes T; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B - metabolism; NF-kB; NF-κB protein; Proteins; R&D; receptor I downregulation; Receptor, Transforming Growth Factor-beta Type I - biosynthesis; Receptor, Transforming Growth Factor-beta Type I - metabolism; Receptors, Antigen, T-Cell - immunology; Research & development; Signal Transduction - immunology; Signaling; Statistical analysis; Studies; T cell activation; T cell quiescence; T cell receptors; TCR signaling; TGF-β; Transcription factors; Transforming growth factor; Transforming Growth Factor beta1 - biosynthesis; Transforming Growth Factor beta1 - metabolism; Transforming growth factor-b; China; signaling; T cell activation; receptor I downregulation; autoimmunity; NF-kB; TCR signaling; T cell quiescence; TGF-β; CARD11; IL-6